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Gated SPECT Myocardial Perfusion Imaging, Intraventricular Synchronism, and Cardiac Events in Heart Failure.
MedLine Citation:
PMID:  24686210     Owner:  NLM     Status:  Publisher    
Abstract/OtherAbstract:
PURPOSE: The purpose of this study was to evaluate the ability of rest gated SPECT myocardial perfusion imaging (MPI) and intraventricular synchronism, to identify heart failure (HF) patients most likely to experience cardiac events.
METHODS: We studied 165 patients with left ventricular ejection fraction of less than 40%, who were divided in 2 groups according to the diagnosis of coronary artery disease (group 1: 136 patients) or not (group 2: 29 patients). All underwent a rest gated SPECT MPI.
RESULTS: In 160 patients, the MPI was abnormal. Mean summed rest score was 17 ± 6 (group 1) versus 10 ± 6 (group 2), P < 0.0001. Mean volumes showed a marked ventricular dilation, slightly higher among nonischemic. The mean value of the phase-derived SD was 70 ± 19 (group 1) versus 59 ± 21 degrees (group 2), P = 0.016. The histogram bandwidth showed no significant differences. Forty-four (39%) of 114 patients showed some kind of event during the follow-up. The more frequent events were HF progression (13%) and acute coronary syndrome (11%). The highest odds ratios for prediction of events were 1.91 (phase SD), 1.66 (etiology), and 1.55 (summed rest score), although the association was not significant.
CONCLUSIONS: A rest gated SPECT is a valid approach to identify HF patients most likely to experience cardiac events.
Authors:
Amalia Peix; Jorge Karell; Lydia Rodríguez; Lázaro O Cabrera; Kenia Padrón; Regla Carrillo; Erick Mena; Yoel Fernández
Publication Detail:
Type:  JOURNAL ARTICLE     Date:  2014-3-28
Journal Detail:
Title:  Clinical nuclear medicine     Volume:  -     ISSN:  1536-0229     ISO Abbreviation:  Clin Nucl Med     Publication Date:  2014 Mar 
Date Detail:
Created Date:  2014-4-1     Completed Date:  -     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  7611109     Medline TA:  Clin Nucl Med     Country:  -    
Other Details:
Languages:  ENG     Pagination:  -     Citation Subset:  -    
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