Document Detail

'Gastrospirillum hominis', another gastric spiral bacterium.
MedLine Citation:
PMID:  1611710     Owner:  NLM     Status:  MEDLINE    
'Gastrospirillum hominis' is a 'new' tightly coiled gram-negative bacterium carrying bundles of sheathed polar flagella. It has been rather infrequently detected in antral and, even more rarely, in fundic mucosa samples removed at endoscopy from patients investigated for Helicobacter pylori colonization. Until now, it has remained noncultivable but has successfully been maintained in laboratory mice. Its identity with similar bacteria found in the stomachs of cats, dogs, monkeys, pigs, and other animals is uncertain. It was probably already seen by early investigators in the first half of this century. Preliminary data published in case reports suggest that it is associated with more or less active chronic antral gastritis, that it is restricted to the gastric epithelium, and that it possesses a urease, thus limiting the specificity of urease tests for H. pylori. There is hitherto no solid proof that it can induce inflammation although it seems capable of invading parietal and other glandular cells and causing ultrastructural changes. Similar organisms spontaneously colonizing the stomachs of rhesus monkeys were shown to increase gastric acid secretion.
R Fischer
Publication Detail:
Type:  Comparative Study; Journal Article    
Journal Detail:
Title:  Digestive diseases (Basel, Switzerland)     Volume:  10     ISSN:  0257-2753     ISO Abbreviation:  Dig Dis     Publication Date:  1992  
Date Detail:
Created Date:  1992-07-30     Completed Date:  1992-07-30     Revised Date:  2007-11-15    
Medline Journal Info:
Nlm Unique ID:  8701186     Medline TA:  Dig Dis     Country:  SWITZERLAND    
Other Details:
Languages:  eng     Pagination:  144-52     Citation Subset:  IM    
Landeshygieneinstitut Magdeburg, FRG.
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MeSH Terms
Child, Preschool
Gastric Mucosa / microbiology
Gastritis / microbiology
Helicobacter pylori / isolation & purification
Middle Aged
Pyloric Antrum
Spirillum / isolation & purification*
Stomach / microbiology*
Terminology as Topic

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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