Document Detail

Gastrointestinal viral infections in homosexual men who were symptomatic and seropositive for human immunodeficiency virus.
MedLine Citation:
PMID:  2841379     Owner:  NLM     Status:  MEDLINE    
Gastrointestinal viruses, predominantly rotaviruses and adenoviruses, were detected by enzyme-linked immunosorbent assay, electron microscopy, or cell culture in greater than 50% of two groups of homosexual men with symptomatic human immunodeficiency virus (HIV) infection, who did (54%) or did not (50%) have diarrhea. Lower detection rates were observed in HIV-seronegative (15%) and asymptomatic HIV-seropositive (16%) men. In the patients with diarrhea, 95% of the isolates of virus were found in the most immunosuppressed patients, those patients with AIDS-related complex or opportunistic infections associated with AIDS. High excretion rates of these viruses are probably associated with both anal-oral transmission and immunosuppression. These viruses apparently cause acute episodes or relapses of diarrhea in some patients but may be co-pathogens or noncontributory to chronic diarrhea in others.
A L Cunningham; G S Grohman; J Harkness; C Law; D Marriott; B Tindall; D A Cooper
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Publication Detail:
Type:  Journal Article; Research Support, Non-U.S. Gov't    
Journal Detail:
Title:  The Journal of infectious diseases     Volume:  158     ISSN:  0022-1899     ISO Abbreviation:  J. Infect. Dis.     Publication Date:  1988 Aug 
Date Detail:
Created Date:  1988-09-15     Completed Date:  1988-09-15     Revised Date:  2006-11-15    
Medline Journal Info:
Nlm Unique ID:  0413675     Medline TA:  J Infect Dis     Country:  UNITED STATES    
Other Details:
Languages:  eng     Pagination:  386-91     Citation Subset:  AIM; IM; X    
Department of Virology, Westmead Hospital, Sydney, New South Wales, Australia.
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MeSH Terms
AIDS-Related Complex / complications,  microbiology
Acquired Immunodeficiency Syndrome / complications*,  microbiology
Adenoviridae / isolation & purification
Diarrhea / complications,  microbiology*
Enterovirus / isolation & purification
Feces / microbiology
HIV Seropositivity*
Norwalk virus / isolation & purification
Rotavirus / isolation & purification
Virus Diseases / complications*,  microbiology
Viruses / isolation & purification

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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