Document Detail

Gastrointestinal manifestations of postnatal cytomegalovirus infection in infants admitted to a neonatal intensive care unit over a five year period.
MedLine Citation:
PMID:  15210678     Owner:  NLM     Status:  MEDLINE    
Sixteen cases of postnatal cytomegalovirus (CMV) infection were identified in a neonatal intensive care unit population over a five year period. Eleven of these infants had gastrointestinal signs at the time of presentation. These ranged from minor and transient (abdominal distension and enteral feed intolerance) to severe and life threatening (protein losing enteropathy, diarrhoea, and hypernatraemic dehydration). An initial diagnosis of necrotising enterocolitis was common, but no infant showed intestinal or hepatic portal pneumatosis. The gestational age of the infants was 24-38 weeks. All had received fresh maternal breast milk. It is suggested that CMV enteritis is added to the spectrum of clinical manifestations of postnatal CMV infection. Signs suggestive of necrotising enterocolitis with atypical features should prompt investigations for CMV infection.
J L Y Cheong; F M Cowan; N Modi
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Publication Detail:
Type:  Journal Article; Review    
Journal Detail:
Title:  Archives of disease in childhood. Fetal and neonatal edition     Volume:  89     ISSN:  1359-2998     ISO Abbreviation:  Arch. Dis. Child. Fetal Neonatal Ed.     Publication Date:  2004 Jul 
Date Detail:
Created Date:  2004-06-22     Completed Date:  2004-07-19     Revised Date:  2008-11-20    
Medline Journal Info:
Nlm Unique ID:  9501297     Medline TA:  Arch Dis Child Fetal Neonatal Ed     Country:  England    
Other Details:
Languages:  eng     Pagination:  F367-9     Citation Subset:  AIM; IM    
Division of Paediatrics, Obstetrics and Gynaecology, Faculty of Medicine, Imperial College, 369 Fulham Road, London SW10 9NH, UK.
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MeSH Terms
Cytomegalovirus Infections / complications*,  epidemiology
Gastrointestinal Diseases / epidemiology,  virology*
Hospitalization / statistics & numerical data
Intensive Care, Neonatal / statistics & numerical data
London / epidemiology
Milk, Human

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