Document Detail

Gastrointestinal manifestations of food allergies.
MedLine Citation:
PMID:  21453809     Owner:  NLM     Status:  In-Data-Review    
The rates of eosinophilic gastrointestinal disorders appear to be increasing. The most common of these is eosinophilic esophagitis (EoE) which is a clinicopathologic condition consisting of characteristic symptoms and endoscopic features accompanied by a pan-esophageal, acid resistant epithelial eosinophilia of greater than equal to 15 per high power field. Typical symptoms include dysphagia and abdominal pain. Typical endoscopic features include pallor, plaques, furrows, concentric rings. Complications include food impactions and strictures. EoE resolution with food elimination diets provides evidence that EoE is a food-antigen driven process. In vitro and microarray studies have identified specific immunologic factors underlying EoE pathogenesis. Other gastrointestinal manifestations of food intolerances/allergy include food protein induced enterocolitis syndrome.
Jaime Liou Wolfe; Seema S Aceves
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Pediatric clinics of North America     Volume:  58     ISSN:  1557-8240     ISO Abbreviation:  Pediatr. Clin. North Am.     Publication Date:  2011 Apr 
Date Detail:
Created Date:  2011-04-01     Completed Date:  -     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  0401126     Medline TA:  Pediatr Clin North Am     Country:  United States    
Other Details:
Languages:  eng     Pagination:  389-405     Citation Subset:  AIM; IM    
Copyright Information:
Copyright © 2011 Elsevier Inc. All rights reserved.
Division of Gastroenterology, Department of Surgery, Children's National Medical Center, Washington, DC, USA.
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