| Gastrointestinal manifestations of food allergies. | |
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MedLine Citation:
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PMID: 21453809 Owner: NLM Status: In-Data-Review |
Abstract/OtherAbstract:
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The rates of eosinophilic gastrointestinal disorders appear to be increasing. The most common of these is eosinophilic esophagitis (EoE) which is a clinicopathologic condition consisting of characteristic symptoms and endoscopic features accompanied by a pan-esophageal, acid resistant epithelial eosinophilia of greater than equal to 15 per high power field. Typical symptoms include dysphagia and abdominal pain. Typical endoscopic features include pallor, plaques, furrows, concentric rings. Complications include food impactions and strictures. EoE resolution with food elimination diets provides evidence that EoE is a food-antigen driven process. In vitro and microarray studies have identified specific immunologic factors underlying EoE pathogenesis. Other gastrointestinal manifestations of food intolerances/allergy include food protein induced enterocolitis syndrome. |
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Authors:
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Jaime Liou Wolfe; Seema S Aceves |
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Publication Detail:
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Type: Journal Article |
Journal Detail:
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Title: Pediatric clinics of North America Volume: 58 ISSN: 1557-8240 ISO Abbreviation: Pediatr. Clin. North Am. Publication Date: 2011 Apr |
Date Detail:
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Created Date: 2011-04-01 Completed Date: - Revised Date: - |
Medline Journal Info:
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Nlm Unique ID: 0401126 Medline TA: Pediatr Clin North Am Country: United States |
Other Details:
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Languages: eng Pagination: 389-405 Citation Subset: AIM; IM |
Copyright Information:
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Copyright © 2011 Elsevier Inc. All rights reserved. |
Affiliation:
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Division of Gastroenterology, Department of Surgery, Children's National Medical Center, Washington, DC, USA. |
Export Citation:
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From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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