| Gastrointestinal malformations in two infants born to women with hyperthyroidism untreated in the first trimester. | |
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MedLine Citation:
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PMID: 12660909 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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We report two infants with gastrointestinal anomalies: one with esophageal atresia and tracheo-esophageal fistula and the other with biliary tree atresia, born to hyperthyroid women diagnosed and treated with methimazole after 14 weeks' gestation. Euthyroidism was documented in both infants. These cases raise the issue of whether untreated hyperthyroidism and not methimazole intake is the teratogen. |
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Authors:
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Muhieddine Seoud; Anwar Nassar; Ihab Usta; Mohammad Mansour; Ibrahim Salti; Khaled Younes |
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Publication Detail:
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Type: Case Reports; Journal Article |
Journal Detail:
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Title: American journal of perinatology Volume: 20 ISSN: 0735-1631 ISO Abbreviation: Am J Perinatol Publication Date: 2003 Feb |
Date Detail:
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Created Date: 2003-03-27 Completed Date: 2003-07-07 Revised Date: 2004-11-17 |
Medline Journal Info:
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Nlm Unique ID: 8405212 Medline TA: Am J Perinatol Country: United States |
Other Details:
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Languages: eng Pagination: 59-62 Citation Subset: IM |
Affiliation:
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Obstetrics and Gynecology, The American University of Beirut Medical Center, New York, New York 10022, USA. |
Export Citation:
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APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
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Abnormalities, Multiple
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chemically induced,
etiology* Adolescent Adult Antithyroid Agents / administration & dosage, adverse effects Biliary Atresia / chemically induced, etiology*, surgery Digestive System / drug effects Digestive System Abnormalities* Esophageal Atresia / chemically induced, etiology*, surgery Female Humans Hyperthyroidism / complications*, drug therapy Infant, Newborn Methimazole / administration & dosage, adverse effects Pregnancy Pregnancy Complications / drug therapy* Time Factors Tracheoesophageal Fistula / chemically induced, etiology*, surgery Treatment Outcome |
| Chemical | |
Reg. No./Substance:
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0/Antithyroid Agents; 60-56-0/Methimazole |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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