Document Detail

Gastrointestinal hormones.
MedLine Citation:
PMID:  356498     Owner:  NLM     Status:  MEDLINE    
The chemistry, localisation, release and effects of gastrointestinal hormones and some related peptides are surveyed. Their main presumed physiologic actions are: gastric acid and pepsin secretion are stimulated by gastrin and to a less degree by secretin. Acid secretion is inhibited by bulbo-enterogastrone and GIP. Biliary water and electrolytes are augmented by gastrin, CCK-PZ, secretin and VIP and inhibited by Substance P. Pancreatic bicarbonate and enzyme secretions are stimulated by secretin and CCK-PZ, especially in combination. Lower oesophageal and antral motility and tonus are elevated following gastrin and motilin; the gallbladder and small intestine empty following CCK. Gastrin regulates gastrointestinal, and CCK pancreatic, tissue growth. Somatostatin inhibits all gut hormones. All peptides are vasoactive within the splanchnic area, each one in a specific manner.
L Thulin; C Johansson
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Publication Detail:
Type:  Journal Article; Review    
Journal Detail:
Title:  Acta chirurgica Scandinavica. Supplementum     Volume:  482     ISSN:  0301-1860     ISO Abbreviation:  Acta Chir Scand Suppl     Publication Date:  1978  
Date Detail:
Created Date:  1978-10-27     Completed Date:  1978-10-27     Revised Date:  2008-11-21    
Medline Journal Info:
Nlm Unique ID:  0370305     Medline TA:  Acta Chir Scand Suppl     Country:  SWEDEN    
Other Details:
Languages:  eng     Pagination:  69-72     Citation Subset:  IM    
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MeSH Terms
Bile / secretion
Chemical Phenomena
Gastric Juice / secretion
Gastrointestinal Hormones* / metabolism,  physiology*,  secretion*
Gastrointestinal Motility
Pancreatic Juice / secretion
Reg. No./Substance:
0/Gastrointestinal Hormones

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