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Gastrointestinal changes associated to heart failure.
MedLine Citation:
PMID:  22527026     Owner:  NLM     Status:  Publisher    
Abstract/OtherAbstract:
Over the last decade, several studies were conducted on the gastrointestinal changes associated to chronic heart failure. This article presents a literature review on the physiopathology and clinical consequences of pathological digestive changes of heart failure patients. Structural and functional abnormalities of the gastrointestinal tract, such as edema of absorptive mucosa and intestinal bacterial overgrowth, have been leading to serious clinical consequences. Some of these consequences are cardiac cachexia, systemic inflammatory activation and anemia. These conditions, alone or in combination, may lead to worsening of the pre-existing ventricular dysfunction. Although currently there is no therapy specifically earmarked for gastrointestinal changes associated to heart failure, the understanding of digestive abnormalities is germane for the prevention and management of systemic consequences.
Authors:
Fernando G Romeiro; Katashi Okoshi; Leonardo A M Zornoff; Marina P Okoshi
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Publication Detail:
Type:  JOURNAL ARTICLE    
Journal Detail:
Title:  Arquivos brasileiros de cardiologia     Volume:  98     ISSN:  1678-4170     ISO Abbreviation:  -     Publication Date:  2012 Mar 
Date Detail:
Created Date:  2012-4-24     Completed Date:  -     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  0421031     Medline TA:  Arq Bras Cardiol     Country:  -    
Other Details:
Languages:  SPA; ENG; POR     Pagination:  273-277     Citation Subset:  -    
Affiliation:
Faculdade de Medicina de Botucatu, SP, Brasil.
Vernacular Title:
Alterações gastrointestinais associadas a insuficiência cardíaca.
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