Document Detail

Gastrointestinal bleeding after hepatic transcatheter arterial embolization in patients with hepatocellular carcinoma.
MedLine Citation:
PMID:  8635707     Owner:  NLM     Status:  MEDLINE    
BACKGROUND: Transcatheter arterial embolization is a popular palliative treatment for patients with hepatocellular carcinoma, but the incidence of post-treatment gastrointestinal bleeding is not well-defined. METHODS: We retrospectively analyzed 206 patients with hepatocellular carcinoma who received transcatheter arterial embolization and compared them with 193 patients with hepatocellular carcinoma who underwent angiography along. RESULTS: Twenty-three episodes (8.5%) of gastrointestinal bleeding occurred within 3 months of hepatic transcatheter arterial embolization following 269 procedures involving 206 patients with hepatocellular carcinoma. Eight episodes (3.0%) of esophageal variceal bleeding and 15 episodes (5.5%) of nonvariceal bleeding were found. The sites of the nonvariceal bleeding episodes were the stomach (n = 7), duodenum (n = 5), and colon (n = 3). When compared with other sources, bleeding from esophageal varices took place earlier, required intensive treatment, and led to a higher mortality. Among another 193 patients with hepatocellular carcinoma who received angiography only, 6 patients developed gastrointestinal bleeding within 3 months (3.1%), and all bled from esophageal varices. CONCLUSIONS: This study suggests that esophageal variceal bleeding may occur after both angiography and transcatheter arterial embolization. Nonvariceal bleeding episodes, which were usually milder than episodes of variceal bleeding, may be related to the embolization procedure itself.
D Y Lin; C F Hung; P C Chen; C S Wu
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Publication Detail:
Type:  Comparative Study; Journal Article    
Journal Detail:
Title:  Gastrointestinal endoscopy     Volume:  43     ISSN:  0016-5107     ISO Abbreviation:  Gastrointest. Endosc.     Publication Date:  1996 Feb 
Date Detail:
Created Date:  1996-07-10     Completed Date:  1996-07-10     Revised Date:  2009-11-03    
Medline Journal Info:
Nlm Unique ID:  0010505     Medline TA:  Gastrointest Endosc     Country:  UNITED STATES    
Other Details:
Languages:  eng     Pagination:  132-7     Citation Subset:  IM    
Department of Gastroenterology and Radiology, Chang Gung Memorial Hospital Linko Medical Center, Taipei, Taiwan.
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MeSH Terms
Aged, 80 and over
Carcinoma, Hepatocellular / complications,  radiography,  therapy*
Embolization, Therapeutic / adverse effects*
Endoscopy, Gastrointestinal
Follow-Up Studies
Gastrointestinal Hemorrhage / etiology*
Liver Neoplasms / complications,  radiography,  therapy*
Middle Aged
Palliative Care
Retrospective Studies

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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