Document Detail


Gastrointestinal amyloidosis secondary to hypersensitivity vasculitis presenting with intestinal pseudoobstruction.
MedLine Citation:
PMID:  9724175     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
A 22-year-old woman developed sudden hepatic encephalopathy and severe intestinal bleeding. She was diagnosed with acute fatty liver and hypersensitivity vasculitis and was successfully treated with whole plasma exchange, methylprednisolone pulse therapy, and transcatheter arterial embolization. Twenty-seven months later, she began complaining of lower abdominal fullness, tenderness, and nausea and vomiting. Histologic examination showed that she had developed gastrointestinal and renal amyloidosis with intestinal pseudoobstruction and proteinuria. The immunohistochemical study of the stomach, rectum, and kidney with anti-amyloid A fluorescent antibody showed that the systemic amyloid deposit was secondary to her underlying disease. This is the first report of amyloidosis occurring secondary to hypersensitivity vasculitis.
Authors:
K Hiramatsu; S Kaneko; Y Shirota; M Matsuda; K Kaji; Y Kitano; N Ikeda; S Terasaki; H Kawai; A Shimoda; H Yokoyama; E Matsushita; T Urabe; K Kobayashi
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Publication Detail:
Type:  Case Reports; Journal Article    
Journal Detail:
Title:  Digestive diseases and sciences     Volume:  43     ISSN:  0163-2116     ISO Abbreviation:  Dig. Dis. Sci.     Publication Date:  1998 Aug 
Date Detail:
Created Date:  1998-09-16     Completed Date:  1998-09-16     Revised Date:  2009-11-19    
Medline Journal Info:
Nlm Unique ID:  7902782     Medline TA:  Dig Dis Sci     Country:  UNITED STATES    
Other Details:
Languages:  eng     Pagination:  1824-30     Citation Subset:  AIM; IM    
Affiliation:
First Department of Internal Medicine, Kanazawa University School of Medicine, Ishikawa, Japan.
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MeSH Terms
Descriptor/Qualifier:
Adult
Amyloidosis / diagnosis,  etiology*
Female
Gastrointestinal Diseases / diagnosis,  etiology*
Humans
Intestinal Pseudo-Obstruction / etiology*
Vasculitis, Leukocytoclastic, Cutaneous / complications*,  diagnosis

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