Document Detail


Gastrointestinal surgery: cardiovascular risk reduction and improved long-term survival in patients with obesity and diabetes.
MedLine Citation:
PMID:  23054662     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
Whereas the initial focus of bariatric surgery primarily focused on weight loss and was considered by many clinicians and the public as a cosmetic-driven procedure, this surgical therapy is now recognized as a successful approach to reducing cardiovascular disease risk and the only substantial and sustainable weight loss treatment for most severely obese patients. In addition, as a result of the multiple metabolic-related benefits associated with bariatric surgery, efforts to understand physiologic and biochemical mechanisms have led to a dramatic increase in scientific discovery. This review focuses on bariatric research conducted during the past two decades in relation to cardiovascular disease risk and the effects of this surgical therapy on diabetes. Cardiovascular and diabetes mortality and morbidity associated with bariatric surgery are reviewed. The opportunity for bariatric (and/or metabolic) surgery to provide a preventive strategy for cardiovascular disease and diabetes as well as treatment therapy is presented for clinical consideration.
Authors:
Ted D Adams; Lance E Davidson; Sheldon E Litwin; Steven C Hunt
Publication Detail:
Type:  Journal Article; Research Support, N.I.H., Extramural; Review    
Journal Detail:
Title:  Current atherosclerosis reports     Volume:  14     ISSN:  1534-6242     ISO Abbreviation:  Curr Atheroscler Rep     Publication Date:  2012 Dec 
Date Detail:
Created Date:  2012-10-29     Completed Date:  2013-05-09     Revised Date:  2013-07-19    
Medline Journal Info:
Nlm Unique ID:  100897685     Medline TA:  Curr Atheroscler Rep     Country:  United States    
Other Details:
Languages:  eng     Pagination:  606-15     Citation Subset:  IM    
Affiliation:
Division of Cardiovascular Genetics, Department of Internal Medicine, University of Utah School of Medicine, Salt Lake City, UT 84108, USA. ted.adams@utah.edu
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MeSH Terms
Descriptor/Qualifier:
Bariatric Surgery / methods*
Cardiovascular Diseases / complications,  mortality,  prevention & control*
Diabetes Mellitus, Type 2 / complications*,  mortality
Humans
Obesity / complications*,  mortality
Risk Factors
Weight Loss / physiology*
Grant Support
ID/Acronym/Agency:
DK-55006/DK/NIDDK NIH HHS; M01 RR000064/RR/NCRR NIH HHS; M01-RR00064/RR/NCRR NIH HHS; R01 DK055006/DK/NIDDK NIH HHS

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