Document Detail

Gastroesophagopharyngeal reflux in patients with contact granuloma: a prospective controlled study.
MedLine Citation:
PMID:  11860073     Owner:  NLM     Status:  MEDLINE    
The aim of this study was to compare the incidences of gastroesophagopharyngeal reflux in patients with contact granuloma and healthy controls. A 24-hour ambulatory esophagopharyngeal pH monitoring technique was used to measure reflux parameters in the pharynx and distal esophagus. Pharyngeal acid reflux events occurred in 17 of 26 granuloma patients (1 to 20 episodes per patient) and 5 of 19 controls (1 to 8 episodes per patient). The reflux episodes were typically short and occurred predominantly in an upright position. A comparison between the groups showed a significant difference in the number of pharyngeal reflux episodes (p = .009) and in the total time of pH below 4 (p = .006). On the other hand, we found no significant differences in any esophageal reflux parameters, except for the percentage of distal esophageal reflux episodes that reached the pharynx (p = .006). In this study, pharyngeal acid exposure was significantly more prevalent in patients with contact granuloma than in healthy controls.
Riitta Ylitalo; Stig Ramel
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Publication Detail:
Type:  Journal Article; Research Support, Non-U.S. Gov't    
Journal Detail:
Title:  The Annals of otology, rhinology, and laryngology     Volume:  111     ISSN:  0003-4894     ISO Abbreviation:  Ann. Otol. Rhinol. Laryngol.     Publication Date:  2002 Feb 
Date Detail:
Created Date:  2002-02-25     Completed Date:  2002-03-07     Revised Date:  2006-11-15    
Medline Journal Info:
Nlm Unique ID:  0407300     Medline TA:  Ann Otol Rhinol Laryngol     Country:  United States    
Other Details:
Languages:  eng     Pagination:  178-83     Citation Subset:  AIM; IM    
Department of Logopedics and Phoniatrics, Huddinge University Hospital and Karolinska Institute, Stockholm, Sweden.
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MeSH Terms
Esophagus / metabolism,  physiopathology
Gastroesophageal Reflux / complications*,  diagnosis
Granuloma, Laryngeal / complications*,  diagnosis
Hydrogen-Ion Concentration
Middle Aged
Monitoring, Ambulatory
Pharynx / metabolism
Prospective Studies
Corrected and Republished In:
Ann Otol Rhinol Laryngol. 2002 May;111(5 Pt 1):441-6   [PMID:  12018329 ]

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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