Document Detail

Gastroesophageal reflux studies using milk in infants and children - the need for multiple views.
MedLine Citation:
PMID:  21849926     Owner:  NLM     Status:  Publisher    
The aim of this study was to assess the value of multiple acquisitions in detecting position-related gastroesophageal reflux (GER). We retrospectively reviewed milk scans of 105 patients with suspected GER and possible lung complications. After 2 h of fasting, 11.4 MBq Tc-99m-sulfur colloid was given to the patient orally along with formula or milk (infants). Without sedation in most patients, serial images (30 s each for 15 frames=8 min) were acquired in the supine, prone, right-side down, and left-side down positions. If reflux was detected in one position, before proceeding to the next position the patient was given water or milk to clear the esophagus.The study was considered positive if the activity reappeared in the esophagus. Anterior and posterior chest images were obtained after a delay of 2-4 h to detect any pulmonary aspiration. A total of 59 patients (56.2%) tested negatively for GER in all four positions and also showed a negative delayed scan for pulmonary aspiration. In contrast, 46 patients tested positively for GER in variable positions (prone=4, supine=6, left-side down=3, right-side down=12, and in more than one position=21, of which six included the supine position). The percentage yield of a positive GER position-related technique was three-fold that of conventional single supine position. These results may aid a better understanding of the pathophysiology of the disease and the design of preventive and therapeutic measures.
Saleh Othman
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Publication Detail:
Type:  JOURNAL ARTICLE     Date:  2011-8-17
Journal Detail:
Title:  Nuclear medicine communications     Volume:  -     ISSN:  1473-5628     ISO Abbreviation:  -     Publication Date:  2011 Aug 
Date Detail:
Created Date:  2011-8-18     Completed Date:  -     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  8201017     Medline TA:  Nucl Med Commun     Country:  -    
Other Details:
Languages:  ENG     Pagination:  -     Citation Subset:  -    
Department of Radiology and Medical Imaging, King Khalid University Hospital and College Of Medicine, King Saud University, Riyadh, Saudi Arabia.
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