Document Detail


Gastroesophageal reflux in patients with sleep apnea syndrome.
MedLine Citation:
PMID:  8585249     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
Gastroesophageal reflux (GER) may be associated with pulmonary diseases. The aim of this study was to investigate the role of GER in patients with sleep apnea syndrome (SAS). We evaluated, therefore, in patients with SAS the occurrence of GER during simultaneous apnea monitoring, and whether GER is related to the severity of SAS. METHODS: 17 consecutive patients with proven SAS were divided into two groups according to the severity of SAS: (A) apnea index > or = 5 and < 15, n = 8; (B) apnea index > or = 15, n = 9. All patients underwent 24 hours pH-metry in the proximal and distal esophagus and simultaneous apnea monitoring during the night. RESULTS: There was a high occurrence of GER in patients with SAS, but no significant difference was found between the two groups with respect to reflux times at the distal or at the proximal esophageal site. Reflux episodes and apnea periods were not timely correlated. Most of the patients of both groups were obese. CONCLUSIONS: Patients with SAS often have GER. However, there is neither a relation of GER with the severity of SAS nor a timely association between GER- and SAS-episodes. Thus, it is unlikely that there is a direct link between GER and SAS. However, there may be factors predisposing for both diseases.
Authors:
K I Graf; M Karaus; S Heinemann; S Körber; P Dorow; K E Hampel
Related Documents :
23429459 - Use and predictors of oral complementary and alternative medicine by patients with infl...
9278669 - Oesophageal and cardia function in patients with paraoesophageal hiatus hernia.
11805419 - Megaprepuce associated with vesicoureteric reflux.
21262109 - Safety and efficacy of deferasirox in multitransfused indian children with β-thalassae...
30679 - Gastroesophageal reflux and bleeding esophageal varices.
8144049 - Spontaneous bile reflux in the elderly.
24534079 - Thrombotic thrombocytopenic purpura-hemolytic uremic syndrome in relapsing-remitting mu...
15883309 - Generalized arteriopathy in patients with cervical artery dissection.
7114359 - Midline granuloma syndrome: a clinicopathologic study of 13 patients.
Publication Detail:
Type:  Journal Article; Research Support, Non-U.S. Gov't    
Journal Detail:
Title:  Zeitschrift für Gastroenterologie     Volume:  33     ISSN:  0044-2771     ISO Abbreviation:  Z Gastroenterol     Publication Date:  1995 Dec 
Date Detail:
Created Date:  1996-03-21     Completed Date:  1996-03-21     Revised Date:  2009-11-11    
Medline Journal Info:
Nlm Unique ID:  0033370     Medline TA:  Z Gastroenterol     Country:  GERMANY    
Other Details:
Languages:  eng     Pagination:  689-93     Citation Subset:  IM    
Affiliation:
Department of Internal Medicine, Virchow-Klinikum, Humboldt-Universität zu Berlin, Germany.
Export Citation:
APA/MLA Format     Download EndNote     Download BibTex
MeSH Terms
Descriptor/Qualifier:
Adult
Aged
Esophagogastric Junction / physiopathology
Female
Gastric Acidity Determination*
Gastroesophageal Reflux / complications,  diagnosis,  physiopathology*
Humans
Male
Manometry
Middle Aged
Polysomnography*
Sleep Apnea Syndromes / complications,  diagnosis,  physiopathology*

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


Previous Document:  Determination of trans-octadecenoic acids in German margarines, shortenings, cooking and dietary fat...
Next Document:  Non-contact argon gas coagulation in flexible endoscopy of the gastrointestinal tract: in vitro stud...