Document Detail


Gastroesophageal reflux in pediatrics; (patho)physiology and new insights in diagnostics and treatment.
MedLine Citation:
PMID:  22350050     Owner:  NLM     Status:  In-Data-Review    
Abstract/OtherAbstract:
GER is the passage of gastric contents into the esophagus and is referred to as GER disease (GERD) when GER causes troublesome symptoms and/or complications. GERD in infants and children is sometimes difficult to diagnose and even more difficult to treat. The diagnosis of GERD is hampered by the fact that GER symptoms such as irritability and crying, feed refusal and regurgitation are common problems in infants and these symptoms are not specific for GERD. Diagnostic criteria for the objective diagnosis of GERD with commonly used diagnostic tests such as pH-metry, pH-impedance monitoring and endoscopy are poorly or not defined. In this review the current understanding of (patho)physiology of GERD, clinical history in infants and children, new insights in diagnostic modalities and the role of non-pharmacological and pharmacological interventions are discussed.
Authors:
C M Loots; M A Benninga; T I Omari
Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Minerva pediatrica     Volume:  64     ISSN:  0026-4946     ISO Abbreviation:  Minerva Pediatr.     Publication Date:  2012 Feb 
Date Detail:
Created Date:  2012-02-21     Completed Date:  -     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  0400740     Medline TA:  Minerva Pediatr     Country:  Italy    
Other Details:
Languages:  eng     Pagination:  101-19     Citation Subset:  IM    
Affiliation:
Pediatric Gastroenterology and Nutrition, Emma Children Hospital/, Academy Medical Centre, Amsterdam, The Netherland - c.m.loots@amc.nl.
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