Document Detail

Gastroesophageal reflux disease.
MedLine Citation:
PMID:  9848819     Owner:  NLM     Status:  MEDLINE    
Gastroesophageal reflux disease (GERD) is a spectrum of disease that can best be defined as the symptoms and/or signs of esophageal or adjacent organ injury secondary to the reflux of gastric contents into the esophagus or, beyond, into the oral cavity or airways. Injury is defined based on symptoms or organ damage resulting in esophagitis, laryngeal inflammation, or acute and/or chronic pulmonary injury. Though specific studies are lacking, GERD seems to occur more frequently in older people. In general, because it has been present for a longer period of time, older patients will often present with more complicated GERD, including severe erosive esophagitis, peptic stricture, and Barrett's esophagus, a premalignant condition, making treatment of older patients with GERD potentially more difficult and complex. Though it is not usually life-threatening, GERD can have a major effect on patients' well-being and quality of life. This article reviews the presentation, pathophysiology, diagnosis, and treatment of GERD as it relates to the older patient.
P O Katz
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Publication Detail:
Type:  Journal Article; Review    
Journal Detail:
Title:  Journal of the American Geriatrics Society     Volume:  46     ISSN:  0002-8614     ISO Abbreviation:  J Am Geriatr Soc     Publication Date:  1998 Dec 
Date Detail:
Created Date:  1998-12-18     Completed Date:  1998-12-18     Revised Date:  2008-03-10    
Medline Journal Info:
Nlm Unique ID:  7503062     Medline TA:  J Am Geriatr Soc     Country:  UNITED STATES    
Other Details:
Languages:  eng     Pagination:  1558-65     Citation Subset:  IM    
Allegheny University of the Health Sciences and the Comprehensive Chest Pain & Swallowing Center, Allegheny University Hospitals, USA.
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MeSH Terms
Anti-Ulcer Agents / administration & dosage
Antiemetics / administration & dosage
Combined Modality Therapy
Esophagus / pathology
Gastric Acidity Determination
Gastroesophageal Reflux / complications,  diagnosis*,  drug therapy
Reg. No./Substance:
0/Anti-Ulcer Agents; 0/Antiemetics
Comment In:
J Am Geriatr Soc. 1999 Oct;47(10):1273-4   [PMID:  10522968 ]

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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