Document Detail


The Domestic/International Gastroenterology Surveillance Study (DIGEST): design, subjects and methods.
MedLine Citation:
PMID:  10565618     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
BACKGROUND: The Domestic/International Gastroenterology Surveillance Study (DIGEST) was designed to examine the 3-month prevalence of upper gastrointestinal (GI) symptoms internationally and the impact of these symptoms on healthcare usage and quality of life. METHODS: The study sample was derived from the urban, adult (> or = 18 years) population of Canada, Italy, Japan, The Netherlands, Switzerland, the USA and the Nordic countries (Denmark, Finland, Norway and Sweden). Subjects were randomly recruited on a house-to-house basis in all countries except the USA and Italy, where telephone recruitment was carried out. Participants were interviewed in their own homes (house-to-house recruitment) or at a central location (telephone recruitment). The DIGEST questionnaire consisted of two sections. The first was a newly developed questionnaire consisting of 27 questions examining the prevalence, frequency and severity of upper GI symptoms, and their impact on healthcare use and daily activities. It also examined a number of demographic and socioeconomic variables. This part of the questionnaire was evaluated and pilot-tested before commencement of the survey. The second part of the questionnaire consisted of the local language version of the Psychological General Well-Being Index (PGWBI), a validated generic quality-of-life scale. Following completion of the survey, subjects with upper GI symptoms were classified on the basis of their most bothersome symptom into three symptom groups: gastro-oesophageal reflux-like, ulcer-like or dysmotility-like. CONCLUSIONS: Rigorous design, standardization of interview techniques and prior evaluation of the DIGEST questionnaire, provided a firm foundation for reliable data collection, analysis and interpretation.
Authors:
A Eggleston; C Farup; R Meier
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Publication Detail:
Type:  Journal Article; Multicenter Study; Research Support, Non-U.S. Gov't    
Journal Detail:
Title:  Scandinavian journal of gastroenterology. Supplement     Volume:  231     ISSN:  0085-5928     ISO Abbreviation:  Scand. J. Gastroenterol. Suppl.     Publication Date:  1999  
Date Detail:
Created Date:  1999-12-07     Completed Date:  1999-12-07     Revised Date:  2008-02-13    
Medline Journal Info:
Nlm Unique ID:  0437034     Medline TA:  Scand J Gastroenterol Suppl     Country:  NORWAY    
Other Details:
Languages:  eng     Pagination:  9-14     Citation Subset:  IM    
Affiliation:
Janssen Ortho Inc, Toronto, Canada. aeggles1@joica.jnj.com
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MeSH Terms
Descriptor/Qualifier:
Adult
Aged
Canada / epidemiology
Cost of Illness
Dyspepsia / economics,  epidemiology
Epidemiologic Research Design*
Female
Finland / epidemiology
Gastrointestinal Diseases / economics,  epidemiology*
Humans
Italy / epidemiology
Japan / epidemiology
Logistic Models
Male
Middle Aged
Netherlands / epidemiology
Population Surveillance*
Quality of Life
Scandinavia / epidemiology
Switzerland / epidemiology
United States / epidemiology
Urban Population
World Health*

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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