| Gastroenteritis with severe consequences: a case of sotalol-induced torsades de pointes. | |
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MedLine Citation:
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PMID: 20128168 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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We present a case of sotalol-induced prolongation of the QT-interval with torsades de pointes in an octogenarian who was hospitalized because of gastroenteritis causing prerenal acute renal failure. Subsequent accumulation of sotalol caused a severe prolongation of the QT-interval on the surface ECG and ultimately torsades de pointes with loss of consciousness. The patient was successfully treated with temporary cardiac pacing, intravenous magnesium sulfate and definitive withdrawal of sotalol. The electrophysiological basis of the pro-arrhythmic properties of sotalol is reviewed in brief, additional risk factors are identified and treatment is outlined. |
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Authors:
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Vincent Michiels; Hielko Miljoen; Christiaan Vrints |
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Publication Detail:
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Type: Case Reports; Journal Article |
Journal Detail:
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Title: Acta cardiologica Volume: 64 ISSN: 0001-5385 ISO Abbreviation: Acta Cardiol Publication Date: 2009 Dec |
Date Detail:
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Created Date: 2010-02-04 Completed Date: 2010-03-09 Revised Date: - |
Medline Journal Info:
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Nlm Unique ID: 0370570 Medline TA: Acta Cardiol Country: Belgium |
Other Details:
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Languages: eng Pagination: 839-42 Citation Subset: IM |
Affiliation:
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Dept. of Cardiology, Antwerp University Hospital, Antwerp, Belgium. vincent.michiels@uza.be |
Export Citation:
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APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
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Aged, 80 and over Anti-Arrhythmia Agents / adverse effects*, therapeutic use Aortic Valve Insufficiency / drug therapy Bumetanide / adverse effects Cardiac Pacing, Artificial Dehydration / etiology Diuretics / adverse effects Electrocardiography Gastroenteritis / complications* Heart Conduction System / drug effects Humans Kidney / drug effects Kidney Failure, Acute / etiology* Male Respiration, Artificial Sotalol / adverse effects*, therapeutic use Torsades de Pointes / chemically induced*, therapy |
| Chemical | |
Reg. No./Substance:
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0/Anti-Arrhythmia Agents; 0/Diuretics; 28395-03-1/Bumetanide; 3930-20-9/Sotalol |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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