Document Detail

Gastro-intestinal atresias in Finland in 1970-79, indicating time-place clustering.
MedLine Citation:
PMID:  3251006     Owner:  NLM     Status:  MEDLINE    
Information on oesophageal, duodenal and rectal atresias was collected from the hospitals, malformation register and death certificates in Finland from 1970-79. The respective prevalence rates were 4.1, 1.4 and 3.6 per 10,000 births, which are among the highest rates cited in the literature. Mothers of children with oesophageal and duodenal atresias were older than the average for child-bearing women in Finland. The sex ratio (male/female) of rectal atresia patients was 2.4. About 50% of the atresia patients had associated malformations. The data indicated time-spaced clustering for atresias. Furthermore, the cases of oesophageal and duodenal atresias appeared to spread within a time period of 30 days from a province to its neighbouring provinces to the north. Spreading was not observed for rectal atresias but clustering was noted when smaller geographic areas and individual communities were analysed. Occupations involving animal contacts were overpresented among the fathers of atresia patients. The data suggest infective aetiology, probably with no known clinical symptoms and no seasonal patterns.
P Kyyrönen; K Hemminki
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Journal of epidemiology and community health     Volume:  42     ISSN:  0143-005X     ISO Abbreviation:  J Epidemiol Community Health     Publication Date:  1988 Sep 
Date Detail:
Created Date:  1989-07-20     Completed Date:  1989-07-20     Revised Date:  2009-11-18    
Medline Journal Info:
Nlm Unique ID:  7909766     Medline TA:  J Epidemiol Community Health     Country:  ENGLAND    
Other Details:
Languages:  eng     Pagination:  257-65     Citation Subset:  IM    
Institute of Occupational Health, Helsinki, Finland.
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MeSH Terms
Abnormalities, Multiple / epidemiology
Duodenal Obstruction / congenital,  epidemiology*
Esophageal Atresia / epidemiology*
Infant, Newborn
Intestinal Atresia / epidemiology*
Maternal Age
Rectum / abnormalities*
Sex Ratio
Space-Time Clustering

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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