Document Detail


Gastrin-producing ovarian mucinous cystadenomas: a cause of the Zollinger-Ellison syndrome.
MedLine Citation:
PMID:  3187898     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
An ovarian gastrinoma would appear to be an extremely rare cause of the Zollinger-Ellison syndrome. Nevertheless, two consecutive cases of Zollinger-Ellison syndrome seen at our institution each proved to be caused by a gastrin-producing ovarian mucinous cystadenoma. That the ovarian tumor was the source of gastrin production was established by preoperative and postoperative gastrin and gastric secretory studies and by specific immunocytochemistry of the excised tissue. After oophorectomy, each patient was apparently cured of the disease. Ovarian gastrinomas may not be as uncommon as is generally believed and should be considered as a possible cause of the Zollinger-Ellison syndrome in any female patient in whom a primary gastrointestinal or pancreatic tumor cannot be located.
Authors:
J N Primrose; M Maloney; M Wells; O Bulgim; D Johnston
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Publication Detail:
Type:  Case Reports; Journal Article    
Journal Detail:
Title:  Surgery     Volume:  104     ISSN:  0039-6060     ISO Abbreviation:  Surgery     Publication Date:  1988 Nov 
Date Detail:
Created Date:  1988-12-06     Completed Date:  1988-12-06     Revised Date:  2004-11-17    
Medline Journal Info:
Nlm Unique ID:  0417347     Medline TA:  Surgery     Country:  UNITED STATES    
Other Details:
Languages:  eng     Pagination:  830-3     Citation Subset:  AIM; IM    
Affiliation:
University Department of Surgery, General Infirmary, Leeds, U.K.
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MeSH Terms
Descriptor/Qualifier:
Adult
Cystadenoma / complications*,  pathology
Female
Gastrinoma / complications*,  pathology
Gastrins / analysis,  biosynthesis
Humans
Middle Aged
Ovarian Neoplasms / complications*,  pathology
Zollinger-Ellison Syndrome / etiology*,  pathology
Chemical
Reg. No./Substance:
0/Gastrins

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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