Document Detail

Gastric tonometry and prediction of outcome in the critically ill. Arterial to intramucosal pH gradient and carbon dioxide gradient.
MedLine Citation:
PMID:  9244017     Owner:  NLM     Status:  MEDLINE    
Splanchnic ischaemia is thought to be of central importance in the development of multi-organ failure and hence death in critically ill patients. It has been suggested that the arterial to gastric intramucosal pH gradient and the difference in partial pressure of carbon dioxide between gastric mucosa and arterial blood are more sensitive markers of splanchnic ischaemia than gastric intramucosal pH itself and thus should be predictors of mortality in the critically ill. We studied 62 critically ill patients within 6 h of admission to the intensive care unit and found no significant difference at 0, 12 or 24 h after admission to the study in either the arterial to gastric intramucosal pH gradient or the difference in partial pressure of carbon dioxide between gastric mucosa and arterial blood between survivors and nonsurvivors. We conclude that in contrast to gastric intramucosal pH neither the arterial to gastric intramucosal pH gradient nor the difference in partial pressure of carbon dioxide between gastric mucosa and arterial blood distinguish survivors from nonsurvivors.
C D Gomersall; G M Joynt; K M Ho; R J Young; T A Buckley; T E Oh
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Anaesthesia     Volume:  52     ISSN:  0003-2409     ISO Abbreviation:  Anaesthesia     Publication Date:  1997 Jul 
Date Detail:
Created Date:  1997-08-14     Completed Date:  1997-08-14     Revised Date:  2004-11-17    
Medline Journal Info:
Nlm Unique ID:  0370524     Medline TA:  Anaesthesia     Country:  ENGLAND    
Other Details:
Languages:  eng     Pagination:  619-23     Citation Subset:  AIM; IM    
Department of Anaesthesia & Intensive Care, Chinese University of Hong Kong, Prince of Wales Hospital, Shatin, NT, Hong Kong.
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MeSH Terms
Carbon Dioxide / blood*
Critical Illness / therapy*
Gastric Mucosa / metabolism*
Hydrogen-Ion Concentration
Ischemia / diagnosis*
Middle Aged
Partial Pressure
ROC Curve
Splanchnic Circulation
Survival Rate
Reg. No./Substance:
124-38-9/Carbon Dioxide
Comment In:
Anaesthesia. 1998 Jan;53(1):95-7   [PMID:  9505760 ]

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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