| Gastric pH and microflora of normal and diarrhoeic infants. | |
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MedLine Citation:
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PMID: 274 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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The microflora and pH of gastric contents were determined in breast-fed and in bottle-fed normal infants, in well nourished infants with acute diarrhoea and in infants with chronic diarrhoea and protein-calorie malnutrition. The last group of infants was reevaluated after recovery from diarrhoea and protein-calorie malnutrition. A bactericidal pH effect below 2-5 was observed. Bottle-fed controls had low pH values and low bacterial concentrations, whereas infants with chronic diarrhoea and protein-calorie malnutrition had high pH values and bacterial overgrowth, essentially of Gram-negative bacilli. After recovery, the only remaining alteration was the frequent isolation of yeast-like fungi in low concentrations. Infants with acute diarrhoea, except for the isolation more frequently of yeast-like fungi, presented no alterations; this seems to indicate that pH alterations and Gram-negative bacilli overgrowth occurred during the evolution of the disease to a chronic state. Breast-fed normal infants had hydrogen-ion concentrations similar to those of the chronic diarrhoea group, but without Gram-negative bacilli overgrowth, suggesting that other factors, besides pH, regulate bacterial growth in the gastric contents of these groups of infants. |
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Authors:
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H V Maffei; F J Nóbrega |
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Publication Detail:
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Type: Comparative Study; Journal Article |
Journal Detail:
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Title: Gut Volume: 16 ISSN: 0017-5749 ISO Abbreviation: Gut Publication Date: 1975 Sep |
Date Detail:
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Created Date: 1976-02-19 Completed Date: 1976-02-19 Revised Date: 2009-11-18 |
Medline Journal Info:
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Nlm Unique ID: 2985108R Medline TA: Gut Country: ENGLAND |
Other Details:
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Languages: eng Pagination: 719-26 Citation Subset: AIM; IM |
Export Citation:
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| MeSH Terms | |
Descriptor/Qualifier:
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Acute Disease Bacteria / isolation & purification* Breast Feeding Candida albicans / isolation & purification Chronic Disease Diarrhea, Infantile / microbiology* Enterobacteriaceae / isolation & purification Gastric Juice / secretion* Humans Hydrogen-Ion Concentration Infant Pharynx / microbiology Protein-Energy Malnutrition / microbiology Pseudomonas / isolation & purification Staphylococcus / isolation & purification Stomach / microbiology* Streptococcus / isolation & purification |
| Comments/Corrections | |
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