Document Detail


Gastric myoelectric and autonomic activities and dyspeptic symptoms in cardiological syndrome X patients.
MedLine Citation:
PMID:  19051692     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
Syndrome X is defined as anginal chest pain accompanied by objective signs of ischemia on exercise testing but with angiographically normal coronary arteries. The aetiology of this syndrome is still not known. The AIM of this study was to evaluate changes in circadian rhythm of gastric myoelectric activity (MA) and autonomic system (AS) and their correlation with dyspeptic symptoms in SX patients. We studied forty consecutive patients, mean age 46+/-8 yrs with syndrome X and 40 sex-, age- and gender-matched healthy volunteers (47+/-5 yrs). The population of syndrome X patients is heterogeneous combining subgroups with normal and low AS activity with high tonic sympathetic drive. Patients with autonomic dysfunction had a high percent of gastric dysrrhythmia with disturbed sympatho-vagal balance particularly at night. We conclude that dyspeptic symptoms in SX patients with autonomic dysfunction are caused mostly by high adrenergic drive affecting stomach myoelectric activity and inducing gastric dysrrhythmias.
Authors:
Władysława Kolasińska-Kloch; Agata Furgała; Małgorzata Kloch; Jerzy Hybel; Piotr J Thor
Publication Detail:
Type:  Journal Article; Research Support, Non-U.S. Gov't    
Journal Detail:
Title:  Folia medica Cracoviensia     Volume:  48     ISSN:  0015-5616     ISO Abbreviation:  Folia Med Cracov     Publication Date:  2007  
Date Detail:
Created Date:  2008-12-04     Completed Date:  2009-02-19     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  0374617     Medline TA:  Folia Med Cracov     Country:  Poland    
Other Details:
Languages:  eng     Pagination:  45-56     Citation Subset:  IM    
Affiliation:
2nd Cardiology Clinic of Cardiology Institute, Medical College, Jagiellonian University, Cracow, Poland. dubiel@cm-uj.krakow.pl
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MeSH Terms
Descriptor/Qualifier:
Autonomic Nervous System / physiopathology
Circadian Rhythm*
Dyspepsia / diagnosis,  etiology*,  physiopathology
Electrodiagnosis
Female
Humans
Male
Microvascular Angina / complications*,  physiopathology*
Middle Aged
Reference Values
Stomach / physiopathology*

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