Document Detail

Gastric marginal ulcer after pancreaticoduodenectomy with pancreaticogastrostomy due to delayed gastric emptying and Helicobacter pylori infection.
MedLine Citation:
PMID:  22469738     Owner:  NLM     Status:  MEDLINE    
BACKGROUND/AIMS: Marginal ulceration and delayed gastric emptying are considerable problems after pancreaticoduodenectomy. Helicobacter pylori (HP) are well known to be associated with gastritis, gastric ulcer and gastric cancer. Thus, we studied the relationship between marginal ulceration and delayed gastric emptying in the early postoperative period after pancreaticoduodenectomy with pancreaticogastrostomy.
METHODOLOGY: We retrospectively studied 58 patients who underwent pancreaticoduodenectomy with pancreaticogastrostomy. On the basis of the grade of delayed gastric emptying, these patients were divided into 2 groups-WS group; without/with slight delayed gastric emptying and MS group; moderate/severe delayed gastric emptying.
RESULTS: Two patients (3.4%) developed postoperative marginal ulcer, these 2 patients had no HP infection; moreover, they belonged to the MS group. Five patients in the WS group were infected with HP; although, postoperative marginal ulceration did not develop in these 5 patients.
CONCLUSIONS: Delayed gastric emptying might be a stronger promoting factor of postoperative marginal ulcer after pancreaticoduodenectomy with pancreaticogastrostomy rather than HP infection and prevention of delayed gastric emptying is important to reduce the occurrence rate of postoperative marginal ulcer. Our modified subtotal stomach-preserving pancreaticoduodenectomy is a useful procedure for preventing delayed gastric emptying and postoperative marginal ulcer after pancreaticoduodenectomy with pancreaticogastrostomy.
Takatsugu Oida; Hisao Kano; Kenji Mimatsu; Atsushi Kawasaki; Youichi Kuboi; Nobutada Fukino; Kazutoshi Kida; Sadao Amano
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Hepato-gastroenterology     Volume:  59     ISSN:  0172-6390     ISO Abbreviation:  Hepatogastroenterology     Publication Date:  2012 May 
Date Detail:
Created Date:  2012-04-03     Completed Date:  2012-07-02     Revised Date:  2014-07-31    
Medline Journal Info:
Nlm Unique ID:  8007849     Medline TA:  Hepatogastroenterology     Country:  Greece    
Other Details:
Languages:  eng     Pagination:  899-902     Citation Subset:  IM    
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MeSH Terms
Chi-Square Distribution
Gastric Emptying*
Gastroparesis / diagnosis,  etiology*,  physiopathology,  prevention & control
Gastrostomy / adverse effects*
Helicobacter Infections / complications,  microbiology*
Helicobacter pylori / pathogenicity*
Middle Aged
Pancreaticoduodenectomy / adverse effects*
Retrospective Studies
Risk Assessment
Risk Factors
Severity of Illness Index
Stomach Ulcer / etiology*,  microbiology,  prevention & control
Time Factors
Treatment Outcome

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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