| Gastric hepatoid adenocarcinoma with autophagy-related necrosis-like tumor cell death: report of a case. | |
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MedLine Citation:
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PMID: 16971355 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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A case of hepatoid adenocarcinoma of the stomach is presented. The characteristic features of the tumor are summarized on the basis of the authors' experience and the literature. Ultrastructural examination revealed patchy condensations of chromatin throughout the nucleus suggestive of necrosis-like programmed cell death (PCD). These nuclear alterations were associated with the occurrence of vacuoles and lipofuscins, conferring an autophagic phenotype to this PCD. Thus, the case reported here provides an example of autophagic-related necrosis-like PCD. Alternative PCDs are reviewed and their morphologic distinction is discussed. |
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Authors:
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R A Caruso; F Basile; F Fedele; V Zuccalà; C Crisafulli; M G Fracassi; E Quattrocchi; A Venuti; V Fabiano |
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Publication Detail:
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Type: Case Reports; Journal Article; Research Support, Non-U.S. Gov't |
Journal Detail:
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Title: Ultrastructural pathology Volume: 30 ISSN: 1521-0758 ISO Abbreviation: Ultrastruct Pathol Publication Date: 2006 Jul-Aug |
Date Detail:
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Created Date: 2006-09-14 Completed Date: 2006-10-03 Revised Date: 2009-06-26 |
Medline Journal Info:
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Nlm Unique ID: 8002867 Medline TA: Ultrastruct Pathol Country: United States |
Other Details:
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Languages: eng Pagination: 301-7 Citation Subset: IM |
Affiliation:
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Departimento di Patologia Umana, Policlinico Universitario, Messina, Italy. Rosariocaruso@tin.it |
Export Citation:
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APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
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Adenocarcinoma
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metabolism,
pathology*,
physiopathology* Aged Autophagy* Hepatocytes / pathology* Humans Male Microscopy, Electron Necrosis Stomach Neoplasms / metabolism, pathology*, physiopathology* alpha-Fetoproteins / biosynthesis |
| Chemical | |
Reg. No./Substance:
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0/alpha-Fetoproteins |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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