| Gastric emptying of solid food in normal man and after subtotal gastrectomy and truncal vagotomy with pyloroplasty. | |
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MedLine Citation:
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PMID: 830569 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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Alterations in gastric emptying are considered contributory to many sequelae of peptic ulcer surgery. The application of a validated method of firmly tagging solid food has enabled the measurement of the rates and patterns of gastric emptying in normal subjects, subtotal gastrectomy, and vagotomy and pyloroplasty (V&P). Normal persons emptied with a linear pattern at a mean rate of 27.96% per hr. Subtotal gastrectomy patients showed up to three phases in their emptying pattern, which, over all, approximated an exponential pattern with a mean rate constant of 0.030 min-1 and calculated t1/2 of 23.3 min. V&P subjects divided into two groups: (1) slow emptying with a linear pattern and mean rate of 17.64% per hr; (2) rapid emptying with exponential pattern and mean rate constant of 0.039 min-1, t1/2 of 17.7 min. The slow gastric emptying rate and slow passage of chyme through the small intestine in one-half of the V&P group presumably allows greater efficiency of digestion and absorption and may account for the over-all less severe nutritional disturbances after V&P. |
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Authors:
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I L MacGregor; P Martin; J H Meyer |
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Publication Detail:
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Type: Journal Article; Research Support, U.S. Gov't, P.H.S. |
Journal Detail:
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Title: Gastroenterology Volume: 72 ISSN: 0016-5085 ISO Abbreviation: Gastroenterology Publication Date: 1977 Feb |
Date Detail:
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Created Date: 1977-02-26 Completed Date: 1977-02-26 Revised Date: 2006-11-15 |
Medline Journal Info:
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Nlm Unique ID: 0374630 Medline TA: Gastroenterology Country: UNITED STATES |
Other Details:
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Languages: eng Pagination: 206-11 Citation Subset: AIM; IM |
Export Citation:
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APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
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Food Gastrectomy* Humans Pylorus / surgery* Stomach / physiology* Time Factors Vagotomy* |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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