| Gastric emptying in healthy newborns fed an intact protein formula, a partially and an extensively hydrolysed formula. | |
| | |
MedLine Citation:
|
PMID: 18280619 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
|
BACKGROUND & AIMS: Gastric emptying (GE) is influenced by the type of nutrition. The objective of this study was to compare GE in infants fed an intact protein formula (IPF), a partially hydrolysed formula (PHF), and an extensively hydrolysed formula (EHF). METHODS: This was a double-blind, randomized, cross-over study. Following a fasting period of > or = 3 h, 20 healthy newborns were fed IPF, PHF, and EHF containing 50 microl (13)C-octanoic acid (OA). Breath samples were taken before feeding and every 15 min for 4 h thereafter. (13)C-OA breath test was assessed by isotope-ratio mass spectrometry, and GE half-times (t(1/2)) were determined. RESULTS: Seventeen infants with a mean gestational age of 37 wk (range 28-40 wk) and birth weight of 2698 g (range 720-3690 g) completed the study. At study initiation, the mean age was 31 d (range 6 d-13 wk) and the mean weight was 3466 g (range 2100-5700 g). EHF emptied significantly faster than IPF and PHF (medians 46 vs. 55 and 53 min, respectively, Wilcoxon, P<0.05 for both). There was no significant difference between GE of PHF and IPF (Wilcoxon, P=0.2). CONCLUSIONS: EHF may be better tolerated by infants with GE problems. |
| | |
Authors:
|
Sofie Staelens; Mieke Van den Driessche; Denis Barclay; Anne-Lise Carrié-Faessler; Ferdinand Haschke; Kristin Verbeke; Hilde Vandebroek; Karel Allegaert; Bart Van Overmeire; Mieke Van Damme; Gigi Veereman-Wauters |
Related Documents
:
|
8271309 - Retinal morphology and visual pigment levels in 6- and 12-month-old rhesus monkeys fed ... 7770309 - Effect of infant formula on stool characteristics of young infants. 20416019 - Partially hydrolyzed 100% whey protein infant formula and atopic dermatitis risk reduct... 19672279 - Iodine intake in the youngest: impact of commercial complementary food. 23142569 - Maternal familism predicts birthweight and asthma symptoms three years later. 3876419 - Serial serum 25-hydroxyvitamin d and mineral homeostasis in very premature infants fed ... 21391229 - Total brain white matter is a major determinant of iq in adolescents born preterm. 19108959 - Contemporary neonatal outcome following rupture of membranes prior to 25 weeks with pro... 2246699 - Effect of extracorporeal membrane oxygenation on survival of infants with congenital di... |
Publication Detail:
|
Type: Journal Article; Randomized Controlled Trial; Research Support, Non-U.S. Gov't Date: 2008-02-15 |
Journal Detail:
|
Title: Clinical nutrition (Edinburgh, Scotland) Volume: 27 ISSN: 1532-1983 ISO Abbreviation: Clin Nutr Publication Date: 2008 Apr |
Date Detail:
|
Created Date: 2008-04-08 Completed Date: 2008-05-30 Revised Date: - |
Medline Journal Info:
|
Nlm Unique ID: 8309603 Medline TA: Clin Nutr Country: England |
Other Details:
|
Languages: eng Pagination: 264-8 Citation Subset: IM |
Affiliation:
|
Pediatric Gastroenterology and Nutrition, Queen Paola Children's Hospital, ZNA, Lindendreef 1, 2018 Antwerp, Belgium. |
Export Citation:
|
APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
|
Breath Tests
/
methods* Carbon Isotopes Cross-Over Studies Dietary Proteins / metabolism* Double-Blind Method Female Gastric Emptying / drug effects*, physiology* Humans Hydrolysis Infant Infant Food Infant Formula* / administration & dosage, chemistry, metabolism Infant, Newborn Male Octanoic Acids |
| Chemical | |
Reg. No./Substance:
|
0/Carbon Isotopes; 0/Dietary Proteins; 0/Octanoic Acids |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
Previous Document: Further delineation of the association signal on chromosome 5 from the first whole genome associatio...
Next Document: Age-related trends in the timeliness and prediction of medical visits, hospitalizations and deaths d...