Document Detail

Gastric bleeding after endoscopic injection sclerotherapy for esophageal varices may be fatal.
MedLine Citation:
PMID:  1778718     Owner:  NLM     Status:  MEDLINE    
Among 457 Japanese cirrhotic patients with esophageal varices, 28 (6%) bled from the upper gastrointestinal tract after the initial session of endoscopic injection sclerotherapy (EIS); 13 bled during the course of repeated EIS and 15 bled mainly from gastric lesions after eradication of the varices. Of these 28 patients, bleeding from gastritis occurred in 13 (46%), from esophageal varices in 10 (36%), from gastric varices in 4 (14%) and from gastric ulcer in one (4%). Six of 13 patients with gastritis-related bleeding and 3 of 4 patients with gastric variceal bleeding died of uncontrollable hemorrhage complicated liver failure, while 9 of 10 patients with esophageal variceal bleeding were controlled and reinjection was feasible. Ten (36%) of the 28 patients, with Child's grade B or C and severe ascites, died, mainly following bleeding from gastric lesions. This study shows that bleeding from gastric lesions after EIS can be uncontrollable and fatal in patients with poor liver function.
H Higashi; S Kitano; M Hashizume; H Yamaga; H Wada; K Sugimachi
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  International surgery     Volume:  76     ISSN:  0020-8868     ISO Abbreviation:  Int Surg     Publication Date:    1991 Oct-Dec
Date Detail:
Created Date:  1992-03-12     Completed Date:  1992-03-12     Revised Date:  2009-11-11    
Medline Journal Info:
Nlm Unique ID:  0043524     Medline TA:  Int Surg     Country:  ITALY    
Other Details:
Languages:  eng     Pagination:  214-7     Citation Subset:  IM    
Department of Surgery II, Kyushu University, Faculty of Medicine, Fukuoka, Japan.
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MeSH Terms
Esophageal and Gastric Varices / etiology,  therapy*
Gastritis / complications
Gastrointestinal Hemorrhage / etiology,  mortality*,  therapy
Liver Cirrhosis / complications
Middle Aged
Oleic Acids / therapeutic use
Polyethylene Glycols / therapeutic use
Sclerosing Solutions / therapeutic use*
Reg. No./Substance:
0/Oleic Acids; 0/Polyethylene Glycols; 0/Sclerosing Solutions; 3282-75-5/ethanolamine oleate; 9002-92-0/polidocanol

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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