| Gastric acid and serum gastrin response to sham feeding, and the effect of cimetidine on the response to sham feeding in duodenal ulcer patients. | |
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MedLine Citation:
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PMID: 6674915 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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Sham feeding resulted in a significant increase of gastric acid secretion in 12 male patients with duodenal ulcer. No significant change in serum gastrin concentration was produced by sham feeding. Reproducibility of gastric acid response to sham feeding was very good (r = 0.74). The mean peak 30 min acid output amounted to 9.5 +/- 1.0 mmol/30 min following sham feeding. That was 46.5% of the 30 min peak acid output elicited by pentagastrin infusion administered in a dose of 1.5 micrograms/kg/h. Cimetidine in a dose of 2 mg/kg/h almost completely reduced (by 85%) the gastric acid secretion induced by sham feeding. Cimetidine did not cause any change in serum gastrin concentration during and after sham feeding. |
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Authors:
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I Kisfalvi; P Földvári; K Szücs |
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Publication Detail:
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Type: Journal Article |
Journal Detail:
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Title: Acta medica Hungarica Volume: 40 ISSN: 0236-5286 ISO Abbreviation: Acta Med Hung Publication Date: 1983 |
Date Detail:
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Created Date: 1984-05-29 Completed Date: 1984-05-29 Revised Date: 2004-11-17 |
Medline Journal Info:
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Nlm Unique ID: 8400269 Medline TA: Acta Med Hung Country: HUNGARY |
Other Details:
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Languages: eng Pagination: 215-20 Citation Subset: IM |
Export Citation:
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APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
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Adult Cimetidine / pharmacology* Duodenal Ulcer / metabolism* Feeding Behavior / physiology* Gastric Acid / secretion* Gastrins / blood* Humans Male Middle Aged Time Factors |
| Chemical | |
Reg. No./Substance:
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0/Gastrins; 51481-61-9/Cimetidine |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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