Document Detail


Gastric acid secretion in HIV-1 infection.
MedLine Citation:
PMID:  1449140     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
It has been suggested that AIDS patients may have reduced gastric acid output. This is of concern because gastric acid may be required for absorption of oral antifungal agents that are important in AIDS management. The cause as well as the progression of reduced gastric acid output in AIDS patients is unclear. This study investigated gastric acid output in relation to the stage of non-AIDS HIV-1-infected patients. No statistical difference was found between nine control and 26 male HIV-infected subjects in basal acid output, maximal acid output, peak acid output, or fasting serum gastrin, regardless of stage. Likewise, no relationship between stage of HIV infection and gastric acid output was determined. We conclude that there is no impairment in basal and maximally stimulated gastric acid secretion in non-AIDS HIV-1-infected males. In addition, the clinical stage of non-AIDS HIV-1 infection has no effect on gastric acid secretion.
Authors:
R T Shaffer; L J LaHatte; J W Kelly; S Kadakia; J G Carrougher; R F Keate; E C Starnes
Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  The American journal of gastroenterology     Volume:  87     ISSN:  0002-9270     ISO Abbreviation:  Am. J. Gastroenterol.     Publication Date:  1992 Dec 
Date Detail:
Created Date:  1992-12-29     Completed Date:  1992-12-29     Revised Date:  2004-11-17    
Medline Journal Info:
Nlm Unique ID:  0421030     Medline TA:  Am J Gastroenterol     Country:  UNITED STATES    
Other Details:
Languages:  eng     Pagination:  1777-80     Citation Subset:  IM; X    
Affiliation:
Department of Medicine, Brooke Army Medical Center, San Antonio, Texas.
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MeSH Terms
Descriptor/Qualifier:
AIDS Serodiagnosis
Gastric Acid / secretion*
HIV Infections / diagnosis,  metabolism*
HIV-1*
Humans
Male

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