| Gastric acid secretion and gastroduodenal pH after pancreaticogastrostomy in dogs. | |
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MedLine Citation:
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PMID: 8769959 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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Pancreaticogastrostomy has been reintroduced as a useful alternative procedure to pancreaticojejunostomy after Whipple resection or pylorus-preserving pancreaticoduodenectomy because of the very low incidence of leakage and disruption. In this study, gastric acid secretion, serum gastrin level, and 24-hr dual gastroduodenal pH after pancreaticogastrostomy were examined on the assumption that a canine model was a pylorus-preserving pancreaticoduodenectomy. Basal acid output (BAO), maximal acid output (MAO), and dual gastroduodenal pH were measured in eight dogs with gastric fistula. After pancreaticogastrostomy, BAO levels showed a slight increase significantly, but MAO levels showed no change. Serum gastrin levels in the fasting and postprandial states showed the similar patterns between before and after surgery. In the 24-hr dual gastroduodenal pH monitoring, gastric pH and duodenal pH also did not change in the fasting and postprandial states. These results suggested that the maintenance of the normal gastric pH after pancreaticogastrostomy was caused by a little increase of BAO, and the neurohumoral relationship between the stomach, duodenum, and pancreas was preserved even after pancreaticogastrostomy. Therefore, the pancreaticogastrostomy is a recommendable reconstructive procedure physiologically after pylorus-preserving pancreaticoduodenectomy. |
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Authors:
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H Shinchi; S Takao; K Fukura; T Aikou |
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Publication Detail:
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Type: Journal Article |
Journal Detail:
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Title: The Journal of surgical research Volume: 61 ISSN: 0022-4804 ISO Abbreviation: J. Surg. Res. Publication Date: 1996 Feb |
Date Detail:
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Created Date: 1996-12-30 Completed Date: 1996-12-30 Revised Date: 2003-11-14 |
Medline Journal Info:
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Nlm Unique ID: 0376340 Medline TA: J Surg Res Country: UNITED STATES |
Other Details:
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Languages: eng Pagination: 152-8 Citation Subset: IM |
Affiliation:
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First Department of Surgery, Kagoshima University School of Medicine, Japan. |
Export Citation:
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| MeSH Terms | |
Descriptor/Qualifier:
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Anastomosis, Surgical* Animals Dogs Duodenum / metabolism* Eating Gastric Acid / secretion* Gastrins / blood Hydrogen / metabolism Hydrogen-Ion Concentration Male Monitoring, Physiologic Pancreas / surgery* Stomach / metabolism*, surgery* |
| Chemical | |
Reg. No./Substance:
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0/Gastrins; 1333-74-0/Hydrogen |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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