Document Detail

Gastric tube reconstruction by laparoscopy-assisted surgery attenuates postoperative systemic inflammatory response after esophagectomy for esophageal cancer.
MedLine Citation:
PMID:  20703457     Owner:  NLM     Status:  In-Process    
BACKGROUND: Conventional open procedures have been supplanted in part by less invasive approaches, such as laparoscopic surgery developed for treating gastrointestinal malignancies. However, it is unclear whether laparoscopy-assisted gastric tube reconstruction (LAGT) can attenuate the postoperative systemic inflammatory response after esophagectomy for esophageal cancer.
METHODS: We investigated the postoperative clinical course of the systemic inflammatory response syndrome (SIRS) in patients who underwent an esophagectomy for esophageal cancer by LAGT (LAGT group) and gastric tube reconstruction by conventional open surgery (Open group).
RESULTS: Compared with the Open group, the LAGT group had a significantly shorter operative time (539.6 min vs. 639.8 min), shorter duration of postoperative mechanical ventilation (1.1 days vs. 2.8 days), and shorter length of stay in the intensive care unit (2.1 days vs. 4.4 days). The LAGT group also had a significantly shorter SIRS duration (1.4 days vs. 2.7 days), a significantly lower incidence of SIRS, and a smaller number of positive SIRS criteria. Throughout the investigation period, the postoperative white blood cell count was lower in the LAGT group than in the Open group. Additionally, in the LAGT group, the heart rate was lower on each postoperative day (POD), and the respiratory rate was significantly lower on postoperative days (PODs) 1 and 4. There was no difference in postoperative oxygenation, morbidity, and mortality between the groups. The C-reactive protein level on PODs 3 and 4 was significantly lower in the LAGT group than in the Open group.
CONCLUSIONS: Laparoscopy-assisted gastric tube reconstruction significantly attenuates postoperative SIRS, and it is therefore a potentially less invasive surgical procedure.
Hironori Tsujimoto; Satoshi Ono; Hidekazu Sugasawa; Takashi Ichikura; Junji Yamamoto; Kazuo Hase
Related Documents :
1469177 - Prevention of nosocomial infection in critically ill patients by selective decontaminat...
18263687 - Mortality rates for patients with acute lung injury/ards have decreased over time.
18154817 - Extrapulmonary ventilation for unresponsive severe acute respiratory distress syndrome ...
15133467 - Optimum treatment of severe sepsis and septic shock: evidence in support of the recomme...
20619747 - The increase in dural sac area is maintained at 2 years after x-stop implantation for t...
10807527 - Modulation of the sympathovagal balance in drug refractory dilated cardiomyopathy, trea...
Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  World journal of surgery     Volume:  34     ISSN:  1432-2323     ISO Abbreviation:  World J Surg     Publication Date:  2010 Dec 
Date Detail:
Created Date:  2010-11-18     Completed Date:  -     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  7704052     Medline TA:  World J Surg     Country:  United States    
Other Details:
Languages:  eng     Pagination:  2830-6     Citation Subset:  IM    
Department of Surgery, National Defense Medical College, 3-2 Namiki, Tokorozawa, 359-8513, Japan.
Export Citation:
APA/MLA Format     Download EndNote     Download BibTex
MeSH Terms

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

Previous Document:  Posterior-only surgery with strong halo-femoral traction for the treatment of adolescent idiopathic ...
Next Document:  Pancreatoduodenectomy with or without early ligation of the inferior pancreatoduodenal artery: compa...