Document Detail


Gastric emptying time of oral contrast material in children and adolescents undergoing abdominal computed tomography.
MedLine Citation:
PMID:  20410846     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
OBJECTIVES: : Considering the hazards of pulmonary aspiration of oral contrast material (OCM) during general anesthesia, we investigated the gastric emptying time (GET) of OCM in children and adolescents undergoing abdominal computed tomography (CT).
PATIENTS AND METHODS: : Included in the study were 101 consecutive patients ages 3.1 to 17.9 years (mean age 12.2 +/- 3.3 years), who underwent contrast-enhanced abdominal CT for suspected acute appendicitis (n = 90), abdominal trauma (n = 10), or suspected ileus (n = 1). Oral iodinated ioxithalamate was given for bowel opacification. Background data (age, sex, weight, chronic diseases, and medication intake), time of initiation and completion of OCM, and time of CT scanning were recorded. To estimate the GET of OCM, CT images were reviewed to examine whether the stomach was empty or full of OCM at the time of imaging.
RESULTS: : The Kaplan-Meier curve showed that 75% of the patients had OCM in the stomach 48 +/- 5.2 minutes after its completion, 50% after 74 +/- 7.9 minutes, and 25% after 135 +/- 32.5 minutes; 1 patient still had OCM after 162 minutes. Except for the length of time taken to drink the contrast material (< or =90 minutes was associated with slower empting of the stomach; log rank, P = 0.03), GET of OCM was not correlated with sex (P = 0.16), age (P = 0.15), weight (P = 0.13), or type of diagnosis (P = 0.41).
CONCLUSIONS: : Given the variability of GET of OCM and if clinically feasible, we advocate waiting at least 3 hours between completion of OCM ingestion and general anesthesia induction.
Authors:
Sivan Berger-Achituv; Rivka Zissin; Ze'ev Shenkman; Michael Gutermacher; Ilan Erez
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Journal of pediatric gastroenterology and nutrition     Volume:  51     ISSN:  1536-4801     ISO Abbreviation:  J. Pediatr. Gastroenterol. Nutr.     Publication Date:  2010 Jul 
Date Detail:
Created Date:  2010-06-28     Completed Date:  2011-01-12     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  8211545     Medline TA:  J Pediatr Gastroenterol Nutr     Country:  United States    
Other Details:
Languages:  eng     Pagination:  31-4     Citation Subset:  IM    
Affiliation:
Department of Pediatrics, Meir Medical Center, Kfar Saba, affiliated with Sackler Faculty of Medicine, Tel Aviv University, Tel Aviv, Israel.
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MeSH Terms
Descriptor/Qualifier:
Adolescent
Anesthesia, General
Appendicitis / radiography
Child
Child, Preschool
Contrast Media / pharmacokinetics*
Female
Gastric Emptying*
Humans
Ileus / radiography
Iothalamic Acid / administration & dosage,  analogs & derivatives
Kaplan-Meier Estimate
Male
Radiography, Abdominal*
Respiratory Aspiration / prevention & control*
Stomach / radiography
Time Factors
Tomography, X-Ray Computed / methods*
Wounds and Injuries / radiography
Chemical
Reg. No./Substance:
0/Contrast Media; 2276-90-6/Iothalamic Acid; 28179-44-4/ioxitalamic acid

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