| Gas insufflation of minimal preparation CT of the colon reduces false positives. | |
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MedLine Citation:
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PMID: 21224295 Owner: NLM Status: Publisher |
Abstract/OtherAbstract:
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Background: Minimal preparation CT of the colon (MPCT colon) is used for investigation of suspected colorectal cancer in frail and/or elderly patients who would be expected to tolerate laxative bowel preparation poorly. Although it has good sensitivity for colorectal cancer it has a poor specificity. We wished to investigate whether distension of the colon with carbon dioxide alone would reduce the number of false positives, but without making the test arduous or excessively uncomfortable. Methods: 134 patients were recruited and underwent MPCT colon with gas insufflation and antispasmodic. Results were compared with a cohort of 134 patients undergoing standard protocol MPCT colon. The numbers of false positives were compared, as was reader confidence. All trial patients were given a questionnaire documenting their experience. Results: The number of false positives was 15% in the control group and 5% in the trial group; this difference was statistically significant, p  =  0.01. Reader confidence was increased in the trial group. Patient tolerance was good, with 95% saying they would have the test again. Conclusion: Use of gas insufflation and antispasmodic reduces the false positives from 15% to 5% without adversely affecting patient tolerance. |
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Authors:
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A Slater; M North; M Hart; C Ferrett |
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Publication Detail:
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Type: JOURNAL ARTICLE Date: 2011-1-11 |
Journal Detail:
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Title: The British journal of radiology Volume: - ISSN: 1748-880X ISO Abbreviation: - Publication Date: 2011 Jan |
Date Detail:
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Created Date: 2011-1-12 Completed Date: - Revised Date: - |
Medline Journal Info:
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Nlm Unique ID: 0373125 Medline TA: Br J Radiol Country: - |
Other Details:
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Languages: ENG Pagination: - Citation Subset: - |
Affiliation:
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John Radcliffe Hospital, Headley Way, Headington, Oxford OX3 9DZ, UK. |
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From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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