Document Detail

Gas exchange detection of right-to-left shunt in dyspneic patients: report of three cases.
MedLine Citation:
PMID:  16516706     Owner:  NLM     Status:  MEDLINE    
We evaluated three patients with undiagnosed complaints of progressive dyspnea. Based on gas-exchange findings as the initial diagnostic tool, the high ventilatory equivalents for CO2, low sustained end-tidal PCO2, hypoxemia, and central cardiovascular dysfunction during cardiopulmonary exercise testing (CPET) suggested that each had significant pulmonary vasculopathy with right-to-left shunting. The diagnoses of Osler-Rendu-Weber syndrome, ventricular septal defect with Eisenmenger's complex, and hepatopulmonary syndrome were later confirmed by pulmonary angiography, cardiac catheterization, and contrast enhanced echocardiography respectively. We suggest that CPET is an appropriate noninvasive tool to begin and guide the evaluation of undiagnosed dyspnea.
Ming-Lung Chuang; Heng-Chia Chang; Kun-Eng Lim; Janine R E Vintch
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Publication Detail:
Type:  Case Reports; Letter; Research Support, Non-U.S. Gov't    
Journal Detail:
Title:  International journal of cardiology     Volume:  108     ISSN:  0167-5273     ISO Abbreviation:  Int. J. Cardiol.     Publication Date:  2006 Mar 
Date Detail:
Created Date:  2006-03-06     Completed Date:  2006-08-10     Revised Date:  2006-11-15    
Medline Journal Info:
Nlm Unique ID:  8200291     Medline TA:  Int J Cardiol     Country:  Ireland    
Other Details:
Languages:  eng     Pagination:  117-9     Citation Subset:  IM    
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MeSH Terms
Arteriovenous Malformations / complications,  diagnosis
Dyspnea / etiology*,  physiopathology
Eisenmenger Complex / complications,  diagnosis*,  physiopathology
Exercise Test
Heart Septal Defects, Ventricular / complications,  diagnosis*,  physiopathology
Hepatopulmonary Syndrome / complications,  diagnosis*,  physiopathology
Middle Aged
Pulmonary Artery / abnormalities
Pulmonary Gas Exchange*
Pulmonary Veins / abnormalities
Telangiectasia, Hereditary Hemorrhagic / complications,  diagnosis*,  physiopathology

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