Document Detail

Gas chromatographic determination of urinary vanilglycolic acid, vanilglycol, vanilacetic acid and vanillactic acid-chemical parameters for the diagnosis of neurogenic tumours and the evaluation of their treatment.
MedLine Citation:
PMID:  184988     Owner:  NLM     Status:  MEDLINE    
A gas chromatographic method is described for the determination of urinary vanilglycolic acid, vanilglycol, vanilacetic acid and vanillactic acid as their trimethylsilyl derivatives. These metabolites are chemical parameters for the dignosis of neurogenic tumours. Their determination is especially recommended in order to evaluate the effect of the therapy. Results in normals and controls are given. Data in a number of selected patients with neuroblastoma, ganglioneuroma and phaeochromocytoma are presented and discussed.
S K Wadman; D Ketting; P A Voûte
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Clinica chimica acta; international journal of clinical chemistry     Volume:  72     ISSN:  0009-8981     ISO Abbreviation:  Clin. Chim. Acta     Publication Date:  1976 Oct 
Date Detail:
Created Date:  1976-12-30     Completed Date:  1976-12-30     Revised Date:  2007-11-15    
Medline Journal Info:
Nlm Unique ID:  1302422     Medline TA:  Clin Chim Acta     Country:  NETHERLANDS    
Other Details:
Languages:  eng     Pagination:  49-68     Citation Subset:  IM    
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MeSH Terms
Child, Preschool
Chromatography, Gas
Chromatography, Thin Layer
Creatinine / urine
Evaluation Studies as Topic
Flavoring Agents / analogs & derivatives*,  urine
Glycolates / urine
Glycols / urine
Hydroxybenzoic Acids / urine*
Lactates / urine
Neoplasms, Nerve Tissue / diagnosis*,  therapy,  urine
Neuroblastoma / diagnosis,  urine
Spectrometry, Fluorescence
Vanillic Acid / analogs & derivatives,  urine*
Reg. No./Substance:
0/Flavoring Agents; 0/Glycolates; 0/Glycols; 0/Hydroxybenzoic Acids; 0/Lactates; 121-34-6/Vanillic Acid; 60-27-5/Creatinine

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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