| Gardner's syndrome with duodenal adenomas, gastric adenomyoma and thyroid papillary--follicular adenocarcinoma. | |
MedLine Citation:
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PMID: 657934 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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A case of a woman with Gardner's syndrome, originally manifested by multiple adenomatous polyps of the colon, is presented. She underwent subtotal colectomy at 14 years of age. Over the next 15 years she had a composite odontoma, an impacted supernumerary tooth, two epidermal inclusion cysts, multicentric paillary-follicular adenocarcinoma of the thyroid, two tubulovillous adenomas of the duodenum in which argyrophilic cells were a prominent feature, and an adenomyoma of the gastric antrum. The presence of all of these lesions in one patient expands the spectrum of lesions seen with Gardner's syndrome and supports the concept of a generalized abnormality of growth regulation as the cause of the syndrome. |
Authors:
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A A Keshgegian; H T Enterline |
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Publication Detail:
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Type: Case Reports; Journal Article |
Journal Detail:
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Title: Diseases of the colon and rectum Volume: 21 ISSN: 0012-3706 ISO Abbreviation: Dis. Colon Rectum Publication Date: 1978 May-Jun |
Date Detail:
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Created Date: 1978-08-14 Completed Date: 1978-08-14 Revised Date: 2004-11-17 |
Medline Journal Info:
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Nlm Unique ID: 0372764 Medline TA: Dis Colon Rectum Country: UNITED STATES |
Other Details:
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Languages: eng Pagination: 255-60 Citation Subset: IM |
Export Citation:
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| MeSH Terms | |
Descriptor/Qualifier:
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Adenocarcinoma
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pathology* Adenoma / pathology* Adult Duodenal Neoplasms / pathology* Female Humans Intestinal Polyps / genetics, pathology* Neoplasms, Multiple Primary / genetics, pathology* Odontogenic Tumors / genetics, pathology Osteoma / genetics, pathology Pedigree Skin Neoplasms / genetics, pathology Syndrome Thyroid Neoplasms / pathology* |
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