Document Detail

Gangrene of the auricle as the first sign of antiphospholipid antibody syndrome.
MedLine Citation:
PMID:  22124599     Owner:  NLM     Status:  Publisher    
Antiphospholipid syndrome (APS), more common in females, manifests clinically as thrombosis and/or recurrent fetal loss. Hemolytic autoimmune anemia and neurological, cardiac and cutaneous manifestations are common. This is the case report of a male patient whose first manifestation of the disease was gangrene of the auricle. The diagnosis of APS was established by biopsy of the lower limb skin, which showed thrombotic vasculopathy with no evidence of vasculitis. This is one of the two major criteria, which, along with a minor criterion, establishes the diagnosis of APS. Possible differential diagnoses are discussed. The importance of the biopsy in the APS diagnosis of this male patient is emphasized.
Erika Bettini de Sá; Adson da Silva Passos; Mariana Cecconi; Maria Lourdes Peris Barbo; José Eduardo Martinez; Gilberto Santos Novaes
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Publication Detail:
Journal Detail:
Title:  Revista brasileira de reumatologia     Volume:  51     ISSN:  1809-4570     ISO Abbreviation:  -     Publication Date:  2011 Dec 
Date Detail:
Created Date:  2011-11-29     Completed Date:  -     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  0404256     Medline TA:  Rev Bras Reumatol     Country:  -    
Other Details:
Languages:  ENG; POR     Pagination:  658-661     Citation Subset:  -    
Departamento de Morfologia e Patologia, PUC-SP.
Vernacular Title:
Gangrena de pavilhão auricular como primeira manifestação de síndrome do anticorpo antifosfolípide.
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