Document Detail


Ganglioside changes during cell aging in human diploid fibroblast TIG-1.
MedLine Citation:
PMID:  7160447     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
Gangliosides of human diploid fibroblast, TIG-1, derived from fetal lung were analyzed during cell aging. The major gangliosides of TIG-1 cells were GM3 and GD3. During cell aging, GM3 and other gangliosides were decreased or below detection level. Lipid-bound sialic acid per mg protein was 2 micrograms at the early, middle and late passages, but between the middle and late passage it was twofold higher than the other passages.
Authors:
T Ohsawa; Y Nagai
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Publication Detail:
Type:  Journal Article; Research Support, Non-U.S. Gov't    
Journal Detail:
Title:  Experimental gerontology     Volume:  17     ISSN:  0531-5565     ISO Abbreviation:  Exp. Gerontol.     Publication Date:  1982  
Date Detail:
Created Date:  1983-04-07     Completed Date:  1983-04-07     Revised Date:  2007-11-15    
Medline Journal Info:
Nlm Unique ID:  0047061     Medline TA:  Exp Gerontol     Country:  ENGLAND    
Other Details:
Languages:  eng     Pagination:  287-93     Citation Subset:  IM    
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MeSH Terms
Descriptor/Qualifier:
Cell Count
Cell Line
Cell Survival*
Diploidy
Embryo, Mammalian
Fibroblasts / metabolism*
G(M1) Ganglioside / metabolism
G(M3) Ganglioside / metabolism
Gangliosides / metabolism*
Humans
Lung
Chemical
Reg. No./Substance:
0/G(M3) Ganglioside; 0/Gangliosides; 37758-47-7/G(M1) Ganglioside; 62010-37-1/ganglioside, GD3

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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