| Ganciclovir treatment of systemic cytomegalovirus in an immunocompetent host. | |
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MedLine Citation:
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PMID: 9379249 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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Cytomegalovirus (CMV) infects a significant number of otherwise healthy individuals. Although most cases are subclinical and therefore not diagnosed, some patients present with a mononucleosis-type illness. Ganciclovir, an agent effective against CMV, has primarily been studied for use in immunocompromised patients. No formal studies have been done in immunocompetent individuals. We report a case of an otherwise healthy adult female with severe heterophile negative infectious mononucleosis. Her symptoms included high fever, malaise, myalgias, cough, and abdominal pain. Work-up revealed an acute CMV infection. Intravenous ganciclovir was given with dramatic clinical and laboratory improvement. |
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Authors:
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J S Leman; T W Toalson; C G Wlodaver |
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Publication Detail:
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Type: Case Reports; Journal Article |
Journal Detail:
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Title: The Journal of the Oklahoma State Medical Association Volume: 90 ISSN: 0030-1876 ISO Abbreviation: J Okla State Med Assoc Publication Date: 1997 Sep-Oct |
Date Detail:
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Created Date: 1997-11-10 Completed Date: 1997-11-10 Revised Date: 2004-11-17 |
Medline Journal Info:
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Nlm Unique ID: 7503043 Medline TA: J Okla State Med Assoc Country: UNITED STATES |
Other Details:
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Languages: eng Pagination: 367-9 Citation Subset: IM |
Affiliation:
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Oklahoma City Clinic, USA. |
Export Citation:
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APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
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Acute Disease Adult Antiviral Agents / therapeutic use* Cytomegalovirus Infections / drug therapy*, immunology* Female Ganciclovir / therapeutic use* Humans Immunocompetence |
| Chemical | |
Reg. No./Substance:
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0/Antiviral Agents; 82410-32-0/Ganciclovir |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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