Document Detail


Gamma knife radiosurgery using 90 Gy for trigeminal neuralgia.
MedLine Citation:
PMID:  11143234     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
OBJECT: The purpose of this paper was to assess the treatment of trigeminal neuralgia (TN) with the higher than normal dose of 90 Gy. METHODS: Forty-two patients with typical TN were treated over a 3-year period with gamma knife radiosurgery. Every patient received a maximum dose of 90 Gy in a single 4-mm isocenter targeted to the root entry zone of the trigeminal nerve. Thirty of 42 patients had undergone no prior treatments. The median follow-up period was 14 months (range 2-30 months). Thirty-one patients (73.8%) achieved complete relief of pain. Nine patients (21.4%) obtained good pain control. Complications were limited to increased facial paresthesia in seven patients (16.7%) and dysgeusia in four patients (9.5%). CONCLUSIONS: The authors conclude that the use of 90 Gy is a safe and effective dose for the treatment of TN.
Authors:
B Nicol; W F Regine; C Courtney; A Meigooni; M Sanders; B Young
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Journal of neurosurgery     Volume:  93 Suppl 3     ISSN:  0022-3085     ISO Abbreviation:  J. Neurosurg.     Publication Date:  2000 Dec 
Date Detail:
Created Date:  2000-12-15     Completed Date:  2001-01-11     Revised Date:  2004-11-17    
Medline Journal Info:
Nlm Unique ID:  0253357     Medline TA:  J Neurosurg     Country:  United States    
Other Details:
Languages:  eng     Pagination:  152-4     Citation Subset:  AIM; IM    
Affiliation:
Department of Radiation Medicine, University of Kentucky, Lexington, 40506, USA. bnico0@pop.uky.edu
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MeSH Terms
Descriptor/Qualifier:
Adult
Aged
Aged, 80 and over
Female
Follow-Up Studies
Humans
Male
Middle Aged
Radiosurgery*
Reoperation
Spinal Nerve Roots / surgery
Treatment Outcome
Trigeminal Neuralgia / diagnosis,  etiology,  surgery*

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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