| Gamma-hydroxybutyrate withdrawal syndrome: dangerous but not well-known. | |
| | |
MedLine Citation:
|
PMID: 19555805 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
|
Gamma-hydroxybutyrate (GHB) is an endogenous inhibitory neurotransmitter and anesthetic agent that is being abused as a 'club drug.' Withdrawal symptoms after cessation of GHB use are common and depend on the intensity of use. However, GHB withdrawal syndrome and delirium are unfamiliar to most psychiatrists, probably due to the fact that neither textbooks nor guidelines cover the subject. The GHB withdrawal syndrome may have a fulminant course that progresses to delirium. In those severe cases, admission to a general hospital and involvement of a psychiatrist become necessary. We present two cases of severe GHB withdrawal delirium, provide an overview of the literature and conclude with treatment recommendations. |
| | |
Authors:
|
Martijn S van Noorden; Lieselotte C A M van Dongen; Frans G Zitman; Ton A C M Vergouwen |
Related Documents
:
|
2008025 - Fetal alcohol syndrome in adolescents and adults. 6544635 - Sinus node dysfunction. 3784775 - Pineal function during ethanol intoxication, dependence, and withdrawal. 15515485 - Austrian syndrome--autopsy report. 8797535 - Progressive encephalomyelitis with rigidity responsive to plasmapheresis and immunosupp... 8440285 - A neurophysiological study on the p300 component of event-related potentials in hakim-a... |
Publication Detail:
|
Type: Case Reports; Journal Article; Review Date: 2008-12-25 |
Journal Detail:
|
Title: General hospital psychiatry Volume: 31 ISSN: 1873-7714 ISO Abbreviation: Gen Hosp Psychiatry Publication Date: 2009 Jul-Aug |
Date Detail:
|
Created Date: 2009-06-26 Completed Date: 2009-07-30 Revised Date: - |
Medline Journal Info:
|
Nlm Unique ID: 7905527 Medline TA: Gen Hosp Psychiatry Country: United States |
Other Details:
|
Languages: eng Pagination: 394-6 Citation Subset: IM |
Affiliation:
|
Department of Psychiatry, Leiden University Medical Center, Leiden 2333 ZA, The Netherlands. msvannoorden@gmail.com |
Export Citation:
|
APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
|
Adolescent Anti-Anxiety Agents / therapeutic use Delirium / chemically induced*, diagnosis, drug therapy Diagnosis, Differential Disease Progression Female Half-Life Hospitals, General Humans Lorazepam / therapeutic use Male Psychiatry Sodium Oxybate / metabolism, poisoning* Substance Abuse Detection Substance Withdrawal Syndrome / diagnosis, drug therapy, etiology* Substance-Related Disorders / complications* Time Factors Young Adult |
| Chemical | |
Reg. No./Substance:
|
0/Anti-Anxiety Agents; 502-85-2/Sodium Oxybate; 846-49-1/Lorazepam |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
Previous Document: alpha/beta-Arteether-induced mania in a predisposed adolescent.
Next Document: L-Arginine enhances the triglyceride-lowering effect of simvastatin in patients with elevated plasma...