Document Detail

Gamma-hydroxybutyrate (GHB) and gamma-butyrolactone (GBL): analysis of overdose cases reported to the Swiss Toxicological Information Centre.
MedLine Citation:
PMID:  15517507     Owner:  NLM     Status:  MEDLINE    
We analysed 141 cases of Gamma-hydroxybutyric acid (GHB) and Gamma-butyrolactone (GBL) intoxication reported by physicians to the Swiss Toxicological Information Centre between 1995 and 2003. GHB and GBL intoxication are associated with considerable morbidity. Multiple drug use is common. Overdosing frequently results in non-reactive coma, which accounts for the severity of the intoxication and the costs occasioned by management.
Matthias E Liechti; Hugo Kupferschmidt
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Publication Detail:
Type:  Journal Article; Research Support, Non-U.S. Gov't    
Journal Detail:
Title:  Swiss medical weekly     Volume:  134     ISSN:  1424-7860     ISO Abbreviation:  Swiss Med Wkly     Publication Date:  2004 Sep 
Date Detail:
Created Date:  2004-11-01     Completed Date:  2004-12-30     Revised Date:  2011-02-15    
Medline Journal Info:
Nlm Unique ID:  100970884     Medline TA:  Swiss Med Wkly     Country:  Switzerland    
Other Details:
Languages:  eng     Pagination:  534-7     Citation Subset:  IM    
Department of Internal Medicine, University Hospital, Zurich, Switzerland.
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MeSH Terms
4-Butyrolactone / poisoning*
Overdose* / epidemiology,  physiopathology
Sodium Oxybate / poisoning*
Switzerland / epidemiology
Reg. No./Substance:
502-85-2/Sodium Oxybate; 96-48-0/4-Butyrolactone

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