Document Detail

Gametophyte differentiation and imprinting control in plants: Crosstalk between RBR and chromatin.
MedLine Citation:
PMID:  19704913     Owner:  NLM     Status:  PubMed-not-MEDLINE    
The Retinoblastoma (pRb) pathway has been implicated as a convergent regulatory unit in the control of cell cycle and disease. We have shown that a crosstalk between RETINOBLASTOMA RELATED (RBR), the Arabidopsis homologue of pRb, and the genes encoding proteins of the chromatin complexes involved in DNA or histone methylation, controls gametophytic and post-fertilization differentiation events and a subset of imprinting effects. We describe here a plausible model that incorporates several components of the plant Retinoblastoma pathway, thus offering a novel paradigm that merges the traditional cell cycle and the chromatin components in the control of cell differentiation and imprinting.
Amal J Johnston; Wilhelm Gruissem
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Communicative & integrative biology     Volume:  2     ISSN:  1942-0889     ISO Abbreviation:  Commun Integr Biol     Publication Date:  2009  
Date Detail:
Created Date:  2009-08-25     Completed Date:  2011-07-14     Revised Date:  2014-10-09    
Medline Journal Info:
Nlm Unique ID:  101478473     Medline TA:  Commun Integr Biol     Country:  United States    
Other Details:
Languages:  eng     Pagination:  144-6     Citation Subset:  -    
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