Document Detail


Gamete intrafallopian transfer vs superovulation with intrauterine insemination for the treatment of infertility.
MedLine Citation:
PMID:  2632659     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
Superovulation with intrauterine insemination (SO-IUI) has been suggested as an alternative to gamete intrafallopian transfer (GIFT), despite the absence of controlled or comparative trials. We retrospectively analyzed all GIFT and SO-IUI cycles performed concurrently from January 1985 to August of 1987 at a single university center. Pregnancy rates were significantly better for GIFT than SO-IUI (P less than 0.001), with an odds ratio of 3.25 (P = 0.001). Stepwise multiple logistic regression identified factors that correlate with pregnancy: absence of endometriosis (P = 0.05), infertility less than 3 years' duration (P = 0.002), TMS greater than or equal to 30 X 10(6) (P = 0.005), and treatment with GIFT rather than SO-IUI (P = 0.001). These data give a first approximation of the increased efficacy of GIFT versus SO-IUI and provide valuable insight into significant confounding variables to be considered when planning a randomized, prospective trial to evaluate these techniques.
Authors:
C R Kaplan; D L Olive; V Sabella; R H Asch; J P Balmaceda; R M Riehl; T R Groff; W N Burns; R S Schenken
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Publication Detail:
Type:  Comparative Study; Journal Article    
Journal Detail:
Title:  Journal of in vitro fertilization and embryo transfer : IVF     Volume:  6     ISSN:  0740-7769     ISO Abbreviation:  J In Vitro Fert Embryo Transf     Publication Date:  1989 Oct 
Date Detail:
Created Date:  1990-05-16     Completed Date:  1990-05-16     Revised Date:  2006-11-15    
Medline Journal Info:
Nlm Unique ID:  8412594     Medline TA:  J In Vitro Fert Embryo Transf     Country:  UNITED STATES    
Other Details:
Languages:  eng     Pagination:  298-304     Citation Subset:  IM    
Affiliation:
Department of Obstetrics and Gynecology, University of Texas Health Science Center, San Antonio 78284.
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MeSH Terms
Descriptor/Qualifier:
Adult
Female
Gamete Intrafallopian Transfer* / statistics & numerical data
Humans
Infertility / therapy*
Insemination, Artificial* / statistics & numerical data
Ovulation*
Pregnancy
Regression Analysis
Retrospective Studies
Superovulation*

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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