Document Detail


Galvanic stimulation in bilateral vestibular failure: 3-D ocular motor effects.
MedLine Citation:
PMID:  10599835     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
Bilateral galvanic vestibular stimulation (GVS) with current intensity of 3 mA was applied at mastoid level in 11 patients with chronic bilateral vestibular failure, in order to determine ocular motor responses by 3-D video-oculography. The following abnormal features were found: (1) a predominantly torsional or mixed torsional-horizontal nystagmus at the onset of stimulation with lower current intensities (1.0-3.0 mA) in nine patients; (2) a reduced amplitude of tonic ocular torsion by about 50% in nine patients (1.3 +/- 0.6 degrees at 3 mA); (3) a nystagmus in the opposite direction at stimulation offset in five patients (rebound); (4) no eye movements at all in a patient with bilateral nerve failure. GVS stimulates the vestibular nerve, thus allowing differentiation of nerve failure from labyrinthine failure. The low thresholds for initiating nystagmus and the rebound, which appear to be the most typical features of bilateral labyrinthine failure, can be explained by central compensation mechanisms.
Authors:
M Dieterich; R Zink; A Weiss; T Brandt
Related Documents :
21253295 - Low levels of pepsinogen i and pepsinogen i/ii ratio are valuable serologic markers for...
22456595 - Pellagra: a clinical, histopathological, and epidemiological study of 7 cases.
8128875 - Assessment of prognosis in sudden deafness.
3178565 - Intratympanic gentamycin therapy for menière's disease placed by tubal catheter with s...
24679895 - Clinical predictors of individual cognitive fluctuations in patients undergoing hemodia...
17186415 - Borderline mental development in a congenital disorder of glycosylation (cdg) type ia p...
Publication Detail:
Type:  Clinical Trial; Journal Article; Research Support, Non-U.S. Gov't    
Journal Detail:
Title:  Neuroreport     Volume:  10     ISSN:  0959-4965     ISO Abbreviation:  Neuroreport     Publication Date:  1999 Nov 
Date Detail:
Created Date:  2000-02-28     Completed Date:  2000-02-28     Revised Date:  2006-11-15    
Medline Journal Info:
Nlm Unique ID:  9100935     Medline TA:  Neuroreport     Country:  ENGLAND    
Other Details:
Languages:  eng     Pagination:  3283-7     Citation Subset:  IM; S    
Affiliation:
Department of Neurology, Ludwig-Maximilians-University, Klinikum Grosshadern, Munich, Germany.
Export Citation:
APA/MLA Format     Download EndNote     Download BibTex
MeSH Terms
Descriptor/Qualifier:
Acceleration
Adult
Aged
Electric Stimulation
Eye Movements / physiology*
Female
Functional Laterality / physiology
Humans
Male
Middle Aged
Nystagmus, Physiologic / physiology
Oculomotor Muscles / innervation,  physiology*
Reflex, Vestibulo-Ocular / physiology
Semicircular Canals / physiology
Vestibular Diseases / diagnosis,  physiopathology*
Vestibular Function Tests / methods*

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


Previous Document:  Inward rectifier potassium channel Kir 2.3 is inhibited by internal sulfhydryl modification.
Next Document:  Glutamate receptors mediate regulation of Na pump isoform activities in neurons.