| Galvanic stimulation in bilateral vestibular failure: 3-D ocular motor effects. | |
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MedLine Citation:
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PMID: 10599835 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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Bilateral galvanic vestibular stimulation (GVS) with current intensity of 3 mA was applied at mastoid level in 11 patients with chronic bilateral vestibular failure, in order to determine ocular motor responses by 3-D video-oculography. The following abnormal features were found: (1) a predominantly torsional or mixed torsional-horizontal nystagmus at the onset of stimulation with lower current intensities (1.0-3.0 mA) in nine patients; (2) a reduced amplitude of tonic ocular torsion by about 50% in nine patients (1.3 +/- 0.6 degrees at 3 mA); (3) a nystagmus in the opposite direction at stimulation offset in five patients (rebound); (4) no eye movements at all in a patient with bilateral nerve failure. GVS stimulates the vestibular nerve, thus allowing differentiation of nerve failure from labyrinthine failure. The low thresholds for initiating nystagmus and the rebound, which appear to be the most typical features of bilateral labyrinthine failure, can be explained by central compensation mechanisms. |
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Authors:
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M Dieterich; R Zink; A Weiss; T Brandt |
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Publication Detail:
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Type: Clinical Trial; Journal Article; Research Support, Non-U.S. Gov't |
Journal Detail:
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Title: Neuroreport Volume: 10 ISSN: 0959-4965 ISO Abbreviation: Neuroreport Publication Date: 1999 Nov |
Date Detail:
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Created Date: 2000-02-28 Completed Date: 2000-02-28 Revised Date: 2006-11-15 |
Medline Journal Info:
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Nlm Unique ID: 9100935 Medline TA: Neuroreport Country: ENGLAND |
Other Details:
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Languages: eng Pagination: 3283-7 Citation Subset: IM; S |
Affiliation:
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Department of Neurology, Ludwig-Maximilians-University, Klinikum Grosshadern, Munich, Germany. |
Export Citation:
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| MeSH Terms | |
Descriptor/Qualifier:
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Acceleration Adult Aged Electric Stimulation Eye Movements / physiology* Female Functional Laterality / physiology Humans Male Middle Aged Nystagmus, Physiologic / physiology Oculomotor Muscles / innervation, physiology* Reflex, Vestibulo-Ocular / physiology Semicircular Canals / physiology Vestibular Diseases / diagnosis, physiopathology* Vestibular Function Tests / methods* |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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