| Gallstones associated with nonalcoholic steatohepatitis (NASH) and metabolic syndrome. | |
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MedLine Citation:
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PMID: 21331995 Owner: NLM Status: Publisher |
Abstract/OtherAbstract:
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Background/aims: We aimed to evaluate the prevalence of non-alcoholic steatohepatitis and metabolic syndrome in patients with symptomatic gallstones undergoing laparoscopic or open cholecystectomy. Methods: A study of 95 patients was performed. Simultaneous liver biopsies were taken during cholecystectomy between 2006 and 2007. There were no postoperative complications. Patients with significant alcohol intake, hepatitis B or C (virus-positive), autoimmune diseases, and Wilson's disease were excluded. Demographics, liver function tests, lipid profile, and ultrasound findings of patients with and without non-alcoholic steatohepatitis were compared. Results: A total of 95 patients completed the study. The mean age was 52.15 years, and 29 patients were male and 66 female. Fifty-two patients (55%) had biopsies compatible with non-alcoholic steatohepatitis. Conclusions: Fifty-five percent of patients with gallbladder stones had associated non-alcoholic steatohepatitis. Awareness of this association may result in an earlier diagnosis. The high prevalence of non-alcoholic steatohepatitis in patients with galbladder stone may justify routine liver biopsy during cholecystectomy to establish the diagnosis and stage and possibly direct therapy. |
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Authors:
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Oktay Yener; Fikret Aksoy; Mustafa Demır; Alp Ozçelık; Canan Erengül |
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Publication Detail:
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Type: JOURNAL ARTICLE |
Journal Detail:
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Title: The Turkish journal of gastroenterology : the official journal of Turkish Society of Gastroenterology Volume: 21 ISSN: 1300-4948 ISO Abbreviation: - Publication Date: 2010 Dec |
Date Detail:
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Created Date: 2011-2-18 Completed Date: - Revised Date: - |
Medline Journal Info:
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Nlm Unique ID: 9515841 Medline TA: Turk J Gastroenterol Country: - |
Other Details:
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Languages: ENG Pagination: 411-415 Citation Subset: - |
Affiliation:
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Department of Surgery, Göztepe Training and Research Hospital, İstanbul. oktayener@gmail.com. |
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From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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