Document Detail

Galantide stimulates sexual behaviour in male rats.
MedLine Citation:
PMID:  7527345     Owner:  NLM     Status:  MEDLINE    
While intracerebroventricular injection of galanin (5 micrograms/rat) inhibited sexual behavior in experienced male rats--without producing any other locomotor or behavioral deficit-, injection of the galanin antagonist, galantide, by the same route (1 or 2 micrograms/rat) stimulated sexual behavior (improving arousal, motivation and performance indexes) and antagonized the effect of galanin. These data further suggest that galanin plays a physiological role in male sexual behavior.
A Benelli; R Arletti; A Bertolini; B Menozzi; R Basaglia; R Poggioli
Related Documents :
18817795 - Reproductive experience alters corticosterone and cbg levels in the rat dam.
6151145 - Ceruletide resembles antipsychotics in rats and schizophrenic patients. preliminary rep...
8098765 - Npc 16377, a potent and selective sigma-ligand. ii. behavioral and neuroprotective prof...
8728545 - Affiliation in periadolescent rats: behavioral and corticosterone response to social re...
3420945 - Effects of 1,2-dibromoethane on isolated hepatocytes: functional alterations and induct...
12047045 - Role of intrarenal angiotensin-converting enzyme in nephropathy of type ii diabetic rats.
Publication Detail:
Type:  Journal Article; Research Support, Non-U.S. Gov't    
Journal Detail:
Title:  European journal of pharmacology     Volume:  260     ISSN:  0014-2999     ISO Abbreviation:  Eur. J. Pharmacol.     Publication Date:  1994 Aug 
Date Detail:
Created Date:  1995-01-09     Completed Date:  1995-01-09     Revised Date:  2006-11-15    
Medline Journal Info:
Nlm Unique ID:  1254354     Medline TA:  Eur J Pharmacol     Country:  NETHERLANDS    
Other Details:
Languages:  eng     Pagination:  279-82     Citation Subset:  IM    
Department of Biomedical Sciences, University of Modena, Italy.
Export Citation:
APA/MLA Format     Download EndNote     Download BibTex
MeSH Terms
Injections, Intraventricular
Motor Activity / drug effects
Neuropeptides / administration & dosage,  pharmacology
Peptides / administration & dosage,  antagonists & inhibitors*,  pharmacology*
Rats, Sprague-Dawley
Sexual Behavior, Animal / drug effects*
Substance P* / analogs & derivatives*
Reg. No./Substance:
0/Neuropeptides; 0/Peptides; 138579-66-5/galantide; 33507-63-0/Substance P; 88813-36-9/Galanin

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

Previous Document:  NG-Nitro-L-arginine protects against ischaemia-induced increases in nitric oxide and hippocampal neu...
Next Document:  Hsp70: a carrier molecule with built-in adjuvanticity.