Document Detail


Galantide stimulates sexual behaviour in male rats.
MedLine Citation:
PMID:  7527345     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
While intracerebroventricular injection of galanin (5 micrograms/rat) inhibited sexual behavior in experienced male rats--without producing any other locomotor or behavioral deficit-, injection of the galanin antagonist, galantide, by the same route (1 or 2 micrograms/rat) stimulated sexual behavior (improving arousal, motivation and performance indexes) and antagonized the effect of galanin. These data further suggest that galanin plays a physiological role in male sexual behavior.
Authors:
A Benelli; R Arletti; A Bertolini; B Menozzi; R Basaglia; R Poggioli
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Publication Detail:
Type:  Journal Article; Research Support, Non-U.S. Gov't    
Journal Detail:
Title:  European journal of pharmacology     Volume:  260     ISSN:  0014-2999     ISO Abbreviation:  Eur. J. Pharmacol.     Publication Date:  1994 Aug 
Date Detail:
Created Date:  1995-01-09     Completed Date:  1995-01-09     Revised Date:  2006-11-15    
Medline Journal Info:
Nlm Unique ID:  1254354     Medline TA:  Eur J Pharmacol     Country:  NETHERLANDS    
Other Details:
Languages:  eng     Pagination:  279-82     Citation Subset:  IM    
Affiliation:
Department of Biomedical Sciences, University of Modena, Italy.
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MeSH Terms
Descriptor/Qualifier:
Animals
Female
Galanin
Injections, Intraventricular
Male
Motor Activity / drug effects
Neuropeptides / administration & dosage,  pharmacology
Ovariectomy
Peptides / administration & dosage,  antagonists & inhibitors*,  pharmacology*
Rats
Rats, Sprague-Dawley
Sexual Behavior, Animal / drug effects*
Substance P* / analogs & derivatives*
Chemical
Reg. No./Substance:
0/Neuropeptides; 0/Peptides; 138579-66-5/galantide; 33507-63-0/Substance P; 88813-36-9/Galanin

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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