Document Detail


Galactorrhea and the defective luteal phase of the menstrual cycle.
MedLine Citation:
PMID:  32106     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
Twelve patients with primary infertility due to a defective luteal phase associated with hyperprolactinemia and galactorrhea are reported. All were treated with 2-bromoergocryptine. During the first cycle of therapy, the serum prolactin level decreased in all cases, and galactorrhea disappeared during the second cycle of therapy. Seven women responded to 2-bromoergocryptine, as was reflected in their endometrial biopsies. The remaining five were given clomiphene citrate on the second and sixth days of the next 2-bromoergocryptine cycle. Three of these patients responded favorably to this combined therapy. Six pregnancies were reported during therapy. The results of follow-up after labor or abortion suggested that these cases represent a latent stage of the amenorrhea-galactorrhea syndrome.
Authors:
S el-Mahgoub
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  International journal of gynaecology and obstetrics: the official organ of the International Federation of Gynaecology and Obstetrics     Volume:  16     ISSN:  0020-7292     ISO Abbreviation:  Int J Gynaecol Obstet     Publication Date:    1978-1979
Date Detail:
Created Date:  1979-03-24     Completed Date:  1979-03-24     Revised Date:  2006-07-19    
Medline Journal Info:
Nlm Unique ID:  0210174     Medline TA:  Int J Gynaecol Obstet     Country:  UNITED STATES    
Other Details:
Languages:  eng     Pagination:  124-7     Citation Subset:  IM    
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MeSH Terms
Descriptor/Qualifier:
Adult
Bromocriptine / therapeutic use
Clomiphene / therapeutic use
Drug Therapy, Combination
Female
Galactorrhea / complications*
Humans
Infertility, Female / drug therapy,  etiology*
Lactation Disorders / complications*
Luteal Phase
Menstruation Disturbances / complications*,  drug therapy
Pregnancy
Prolactin / blood*
Chemical
Reg. No./Substance:
25614-03-3/Bromocriptine; 9002-62-4/Prolactin; 911-45-5/Clomiphene

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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