Document Detail

Galactorrhea and amenorrhea in burn patients.
MedLine Citation:
PMID:  18403124     Owner:  NLM     Status:  MEDLINE    
INTRODUCTION: Galactorrhea and/or amenorrhea, although uncommonly reported in post-burn patients, is a complex problem to treat. Patient is reluctant to volunteer history of these symptoms, unless asked specifically. AIM: To study profile of adult female patients with galactorrhea and/or amenorrhea in post burn period. MATERIALS AND METHOD: A prospective study of all adult female patients presenting with or detected to have galactorrhea and/or amenorrhea in post burn period was conducted over 6 month's period. Detailed clinical examination, estimation of LH, FSH, Prolactin levels and X-ray of skull was done in all patients. The data collected was analyzed. Patients with hyperprolactinemia and galactorrhea were treated with Bromocriptine for 3 weeks to 3 months. In all patients with amenorrhea, pregnancy was ruled out by gynecological examination and urine pregnancy test. RESULTS: During this period, 30 patients (15.15%) were detected to have galactorrhea and/or amenorrhoea. The extent of burn in these patients was 20-65%of body surface area. Out of 30 patients, 5 had galactorrhea and amenorrhea, 1 galactorrhea alone and 24 had amenorrhea alone. Analysis of voluntary disclosures and detection on interrogation was done. Till the end of study, 4 patients with galactorrhea had complete relief, 2 patients reported reduction in discharge. DISCUSSION: Galactorrhea was distressing for all and was always associated with high prolactine levels .The reverse was not true. All the patients had chest burns besides other body areas. Association was noted between menstrual aberration and ovulatory phase at the time of burn. CONCLUSION: Galactorrhea and menstrual disturbances do exist in female patients in reproductive age group in post burn period and patients should be especially interrogated for these symptoms by the burn care providers.
Navin Goyal; Madhuri A Gore; Ravi Shankar
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Publication Detail:
Type:  Journal Article     Date:  2008-04-09
Journal Detail:
Title:  Burns : journal of the International Society for Burn Injuries     Volume:  34     ISSN:  0305-4179     ISO Abbreviation:  Burns     Publication Date:  2008 Sep 
Date Detail:
Created Date:  2008-07-28     Completed Date:  2008-12-23     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  8913178     Medline TA:  Burns     Country:  England    
Other Details:
Languages:  eng     Pagination:  825-8     Citation Subset:  IM    
Department of General Surgery, LTM Medical College, Sion, Mumbai, India.
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MeSH Terms
Amenorrhea / diagnosis,  psychology*
Bromocriptine / therapeutic use
Burns / complications*,  psychology
Follicle Stimulating Hormone
Galactorrhea / diagnosis,  drug therapy,  psychology*
Hormone Antagonists / therapeutic use
Prolactin / blood
Prospective Studies
Skin / injuries*
Thoracic Injuries / complications*
Treatment Outcome
Young Adult
Reg. No./Substance:
0/Hormone Antagonists; 25614-03-3/Bromocriptine; 9002-62-4/Prolactin; 9002-68-0/Follicle Stimulating Hormone

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